Active learning questions 1

Question 1

Which statement about Na/K ATPase is true?
1)The pump maintains intracellular K+ at a low concentration
2)The pump will work in the absence of ATP
3)The net effect of transport is to make the inside of the cell more negative
4)The pump maintains intracellular Na+ at a high concentration

Answer 1

3)The net effect of transport is to make the inside of the cell more negative

Question 2

Which statement about Na/Ca exchanger is true?
1) The stoichometry of 3Na+:1Ca2+ enables gradient to be magnified 3 fold
2) Enables it to be magnified 1000 fold
3) Transport by the exchanger is independent of membrane potential
4) The exchanger normally moves Na+ out of the cell

Answer 2

2) Enables it to be magnified 1000 fold

Question 3

Which of these is true?
1) IP3 and ryanodine are present in the cell membrane
2) Ryanodine receptors are stimulated by caffeine
3) Emptying of calcium stores stimulates the store operated calcium channels
4)The plasma membrane Ca2+ ATPase (PMCA) also act to refill calcium stores

Answer 3

2 and 3

Question 4

Which of these statement is true?
1) Flow in the trachea is laminar in nature
2) Flow is laminar when the Reynolds number is less than 1
3) Flow is laminar when the Reynolds is less than 2000
4) Flow is laminar when the Reynolds is greater than 2000

Answer 4

2) Flow is laminar when the Reynolds number is less than 1

Question 5

Which of these happens with respect to total airway resistance in patient with COPD?
1) The resistance of the pharynx-larynx is decreased
2) The resistance of the airways with a diameter greater than 2mm is decreased
3) The resistance of the airways with a diameter greater than 2mm contributes to 40% of the total resistance
4) The resistance of the airways with a diameter less than 2mm is increased

Answer 5

4) The resistance of the airways with a diameter less than 2mm is increased

Question 6

If you have a snorkel on underwater does this increase or decrease dead space?

Answer 6

Increases dead space

Question 7

Activation of the M3 muscarinic receptor on airway smooth muscles causes which of the following changes?
1) release of calcium from IP3 sensitive stores of calcium calmodulin, stimulation of myosin light chain kinase
2) The proaction of cAMP, stimulation of protein kinase A, release of calcium from IP3 sensitive stores and stimulation of myosin light chain kinase
3) Release of cAMP, stimulation of protein kinase A, a decrease in intracellular calcium and inhibition
4) Release of calcium from ryanodine sensitive stores, activation of calcium calmodulin, stimulation of myosin light chain kinase

Answer 7

1) release of calcium from IP3 sensitive stores of calcium calmodulin, stimulation of myosin light chain kinase