Lecture 9 Nerve Impulse conduction Flashcards
What is propagation of AP
Unidirectional (Refractory Period)
What are the Factors affection speed
- Axon diameter
2. myelination
Axon Diameter characteristics
Larger Diameter= less resistance —> faster
Small Diameter= more resistance –> slower
what is myelination ?
axons covered with myelin
allows AP ro transmit more efficiently (vs unmyelinated)
What is Myelin
insulating layer of plasma membrane
formed by:
1. schwann cells
2.oligodendrocytes
what are schwann cells
in peripheral nervous system (PNS)
once cell can myelinate only one axon
what are oligodendrocytes
in the CNS
once cell can myelinate several axons
Unmyelinated VS Myelinated axons
Each point along the axon must form an AP
more distance for AP –> slow
rate 2 m/sec
what is myelinated axon conduction
-Voltage regualted gates concentrated on nodes of Ranvier
- Only nodes of ranvier form an AP
*Ions flow through myelinated regions
saltatory propagation : AP jumping from node to node
- Less distance for AP —> fast
Rate: 120 m/ sec
Nodes of Ranvier
unmyelinated regions on axon