Lecture 9: Energy and Enzymes (start of final exam material) Flashcards
What are the 5 important functions energy is used for?
- movement
- chemical reactions
- temperature control
- nerve signals
- cell division/ reproduction
What is the difference between kinetic energy and potential energy
- kinetic: active motion energy
- potential: stored energy
Explain the potential energy in bonds:
- which bonds have the highest PE and the lowest; why?
- what happens to the PE of the products if a chemical reaction creates more polar bonds?
- highest PE: non polar bonds (equal sharing of electrons and long weak bonds) vs lowest PE: polar bonds
- the products have a lower PE
Explain the first law in thermodynamics
- energy in = energy out
Write out the chemical breakdown of glucose
- C6H12O6 + 6O2 6CO2 + 6H2O + 2800kJ
What is enthalpy (H)?
- the total energy in a molecule; most of it is stored potential energy
Explain the change in enthalpy in an:
- exothermic reaction
- endothermic reaction
- exothermic: change in enthalpy is NEGATIVE
- endothermic: change in enthalpy is POSITIVE
Define: entropy (s)
- amount of disorder
What is the Gibbs free energy equation? State the whole equation.
Calculates the energy associated with a chemical reaction that can be used to do work.
delta G = delta H + T(deltaS)
- H is enthalphy, T is temp, S is entropy
Explain the change in entropy in the chemical breakdown of glucose
- entropy increases because more disorder occurs
Explain delta G/ the change in free energy if:
- the products have less free energy than the reactants
- the products have more free energy than the reactants
- what does this mean about the reactions?
- delta G is negative and the reaction is exergonic and spontaneous
- delta G is positive and the reaction is endergonic and non spontaneous
define: exergonic and endergonic reactions;
- what drives endergonic reactions?
exergonic: reaction that releases energy
endergonic: reaction that absorbs energy; driven by ATP
Draw a diagram of the free energy overtime of a spontaneous reaction. Also:
- explain and label delta G, Ea, transition state.
- explain the speed of the reaction and what it is dependent on.
- how can you accelerate the reaction?
- what stabilises the transition state
- see google doc
- speed of reaction may be fast or slow depending on activation energy required
- to accelerate the reaction you must lower the activation energy (with a catalyst)
- enzymes stabilize the transition state
Draw the hydrolysis reaction of ATP and the coupled reaction diagram
- see google doc
explain the metabolic pathway
- reactions are sequential (A–>B–>C–>D)