Lecture 9 Flashcards
1
Q
Epidemic/Outbreak
A
Disease occurrence among a population that is in excess of what is expected in a given place.
2
Q
Cluster
A
Group of cases in a specific time and place that might be more than expected.
3
Q
Endemic
A
Disease or condition present among a population at all times
4
Q
Pandemic
A
A disease or condition that spreads across regions
5
Q
R0
A
- Basic reproduction number
- How many people each infected person will infect (how contagious)
- < 1 the disease is controlled and not spreading too quickly.
6
Q
Plague
A
- Bacteria (gram -)
- Host is a rodent, flea bites rodent and aquires the disease then the flea bites human. Humans can then transfer to others via droplets.
- Flu symptoms, vomiting and swollen lymph nodes.
7
Q
Smallpox
A
- Virus
- Milkmaids who had gotten cowpox where protected from small pox.
- Fatigue, abdominal pain, bumps with clear liquid which begins on face and hands then spread to the rest of the body.
- Person to person via infective droplets.
8
Q
Tuberculosis
A
- Bacteria (gram +)
- Leading causing death from infections disease.
- Slowly waste away, becoming pale and thin before dying.
- Was considered fashionable.
- Usually infects the lungs.
- Chronic back pain (thoracic region)
9
Q
Malaria
A
- Protozoa
- Mosquitos carry and bite people where the parasite enters the blood stream, it will invade red blood cells and destroys it.
- Fatigue, fever, chills, headaches
10
Q
Cholera
A
- Bacteria (gram -)
- Water borne, so drinking contaminated water or food.
- Will invade the small intestine where it released a toxin causing massive fluid loss resulting in shock then death.
11
Q
Influenza
A
- RNA virus
- Muscle aches, fever, chills, fatigue
- Human to human transmission, usually droplet.
12
Q
Pandemics
A
- Asia Flu 1957-1959
- Hong Kong flu 1968
- Swine flu 2009
13
Q
Coronavirus
A
- MERS, SARS and SARS-CoV2 virus
- Droplet and airborne particles spread
- R=2.5-9
- Accesses host cells in the lungs via the receptor for the enzyme
angiotensin-converting enzyme 2 (ACE2). Spike protein attaches to cell and an endosome is released. - Fever, sore throat, loss of taste or smell, tired, headache, diarrhoea
14
Q
HIV/Aids
A
- Virus
- Unprotected sex, needle sharing, blood products.
- Affects T cells and weakens immune system.
15
Q
Measles
A
- RNA virus
- Infectious droplet and airborne spread
- Cough, coryza, conjunctivitis, rash and fatigue.
- Lifelong immunity
16
Q
Mad Cow Disease
A
- Prion (small piece of protein)
- Cattle eat remains of other cattle/sheep as food and humans eat these infected cows.
Mortality rate = 100%
-
17
Q
Rabies
A
- Virus
- Mortality close to 100%
- Neurological symptoms, salivation
- Animal bite
18
Q
Reye Disease
A
- The exact cause is not known, but it often occurs in children recovering from a virus — like chickenpox — especially if aspirin was administered
19
Q
Factors of Influence of Infectious Diseases
A
- Population increases: Poverty, malnutrition, poor sanitation
- Habitat incursion
- Climate change expands habitat of vectors
- Drug resistance; resistance to insecticides
- Mutation enhancement?