Lecture 8 - Mood Disorders (Depressive Disorders) Flashcards
Mood Disorders
also known as affective disorders
- extremes of emotion (or affect) are common to all mood disorders (deep depression or soaring elation)
- other symptoms or co-occurring disorders may also be present, but abnormal mood is the defining feature
types of mood disorders
the two key moods involved are mania and depression
in unipolar depressive disorders the person experiences …
… only depressive episodes
in bipolar disorders the person experiences …
… both manic and depressive episodes
DSM-5 Depressive Disorders
- Disruptive Mood Dysregulation Disorder
- Major Depressive Disorder
- Persistent Depressive Disorder (Dysthymia)
- Premenstrual Dysphoric Disorder
- Substance/Medication-Induced Depressive Disorder
- Depressive Disorder Due to Another Medical Condition
Disruptive Mood Dysregulation Disorder
chronic, severe persistent irritability marked by temper outbursts and persistent irritable or angry mood behavior outbursts for children up to 12 years of age
Premenstrual Dysphoric Disorder
symptoms present in the final week before the onset of menses, start to improve within a few days after the onset of menses and become minimal or absent in the week post menses
new classification of Depressive Disorders in DSM-5
separated from Bipolar and Related Disorders
- previously, these disorders fell under the broad heading of Mood Disorders
features of Depressive Disorders
- sad, empty, or irritable mood
- somatic and cognitive changes that significantly affect the individual’s capacity to function
- they differ across issues of duration, timing, or presumed etiology
the adaptive significance of Depression
- mild, brief depression can be normal and adaptive
- sadness, hopelessness, and pessimism are common human experiences
- mild depression allows us to be still and reflect
Major Depressive Episodes (Major Depressive Disorders)
mood episodes do not have their own diagnostic codes and cannot be diagnosed as separate entities
mood Episodes serve as building blocks for the Disorder diagnoses
- Major Depressive Disorder, single episode (presence of a single Major Depressive Episode)
- Major Depressive Disorder, recurrent (presence of two or more Major Depressive Episodes)
Major Depressive Disorder: DSM-5 Diagnostic Criteria A
five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning: at least one of the symptoms is either 1) depressed mood, or 2) loss of interest or pleasure
- depressed most of the day, nearly every day, as indicated by either subjective report or observation made by others; note: in children and adolescents, can be irritable mood
- markedly diminished interest or pleasure in all, or almost all, activities most of the day, nearly every day (as indicated by either subjective account or observation)
- significant weight loss (when not dieting) or weight gain (e.g. change of more than 5% of body weight in a month), or decrease or increase in appetite nearly every day; note: in children, consider failure to make expected weight gain
- insomnia or hypersomnia nearly every day
- psychomotor agitation or retardation nearly every day (observable by others, not merely subjective feelings of restlessness or being slowed down)
- fatigue or loss of energy nearly every day
- feelings of worthlessness or excessive or inappropriate guilt (which may be delusional) nearly every day (not merely self-reproach or guilt about being sick)
- diminished ability to think or concentrate, or indecisiveness, nearly every day
- recurrent thoughts of death (not just fear of dying), recurrent suicidal ideation w/o a plan, or a specific plan for committing suicide
Major Depressive Disorder: DSM-5 Diagnostic Criteria B
the symptoms cause clinically significant distress or impairment in social, occupational, or other important areas of functioning
Major Depressive Disorder: DSM-5 Diagnostic Criteria C
the episode is not attributable to the physiological effects of a substance or another medical condition
Major Depressive Disorder: DSM-5 Diagnostic Criteria A-C represents a …
… Major Depressive Episode
- “Responses to a significant loss (e.g. bereavement, financial ruin, losses from a natural disaster, a serious medical illness or disability) may include the feelings of intense sadness, rumination about the loss, insomnia, poor appetite, and weight loss noted in Criterion A, which may resemble a depressive episode . Although such symptoms may be understandable or considered appropriate to the loss, the presence of a major depressive episode in addition to the normal response to a significant loss should also be carefully considered. This decision inevitably requires the exercise of clinical judgment based on the individual’s history and the cultural norms of the expression of distress in the context of loss.”
Diagnostic Recording of a Major Depressive Episode
severity/psychosis/course specifier
the diagnostic code for MDD is based on whether this is …
… a single or recurrent episode, current severity, presence of psychotic features and remission status
- mild, moderate, severe, with psychotic features, in partial remission, in full remission
- current severity and psychotic features are only indicated if full criteria are currently met in a MDE
- remission specifiers are only indicated if the full criteria are not currently met for a MDE (2 months duration)
dimensional conceptualization of Severity
severity is based on the number of criterion symptoms, the severity of those symptoms, and the degree of functional disability
- mild, moderate, and severe
mild severity
few if any symptoms in excess of those required to make the diagnosis are present, the intensity of the symptoms is distress but manageable, the symptoms result in minor impairment in social or occupational functioning
moderate severity
the number of symptoms, intensity of symptoms, and/or functional impairment are between those specified “mild” and “severe”
severe severity
the number of symptoms is substantially in excess of that required to make the diagnosis, the intensity of the symptoms is seriously distressing and unmanageable, and the symptoms markedly interfere w/ social and occupational functioning
specifiers of Major Depressive Episode
- DSM-5 specifiers
- w/ melancholic features
- w/ psychotic features
- w/ atypical features
- w/ catatonic features
- w/ seasonal pattern
Major Depressive Episode Specifiers: DSM-5 specifiers
w/ anxious distress, w/ mixed features, w/ melancholic features, w/ atypical features, w/ mo0d congruent psychotic features, w/ catatonia, w/ peri-partum onset, w/ seasonal pattern
Major Depressive Episode Specifiers: w/ melancholic features
3 of the following: early morning awakening, depression worse in the morning, marked psychomotor agitation or retardation, loss of appetite or weight, excessive guilt, qualitatively dif. depressed mood
Major Depressive Episode Specifiers: w/ psychotic features
delusions or hallucinations (usually mood congruent); feelings of guilt and worthlessness common