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Exam 1 FTM > Lecture 8: Epithelial and glands > Flashcards

Lecture 8: Epithelial and glands Flashcards

1
Q

Terminal Bar

A

Basal membrane

Anchors epthelium to connective tissue

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2
Q

Basal Membrane location

A

Between Connective tissue

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3
Q

Basal Lamina

A

Attachment site for overlying epithelial cells and underlying connective tissue

Contains:

  • Laminins
  • IV collagen
  • Proteoglcans and glycoproteins

2 layers:

1) Lamina lucida
2) Lamina densa

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4
Q

External Lamina

A

Basal lamina in nonepithelial cells

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5
Q

Endocrine Glands

Exocrine Glands (Modes)

A

Endocrine Glands:
-Secretes products (hormones) into connective tissue and then enters the bloodstream

Exocrine Glands: Secretes directly onto a surface or through a duct connected to a surface

Exocrine Modes:
1) Metrocrine- Exocytosis of membrane bound vesicles

2) Apocrine- Release at apical surface of plasma membrane
3) Holocrine- Cell death, releases secretory products and cell debris (Ex: explosion)

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6
Q

Identify difference between mucous and serous glands

A

See lecture slides

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7
Q

Zonula Occludens (tight junctions)

A

Sealing of plasma membrane of adjacent cells, separating luminal space from intercellular space and connective tissue

Borders apical cell

Controls passage of molecules between them (AT TOP)

Cell signaling

Contains transmembrane proteins:

1) Occuldens
2) Claudlens

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8
Q

Zonula Adherens

A

Couples the actin cytoskeleton to the plasma membrane

(Cell to cell adhesion, attaching cells)

-CALCIUM DEPENDENT

Transmembrane proteins:
-E-cadherins

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9
Q

Macula Adherens (Desmosomes)

A

Couples INTERMEDIATE FILAMENT to the plasma membrane
(Cell to cell adhesion)

-Calcium dependent

  • Transmembrane proteins:
    1) Desmocollin
    2) Desmoplakins
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10
Q

Gap junction

A

Created channel between two cells that allows for passage of small ions and micromolecules

(IN ZONULA ADHERENS)

  • Transmembrane proteins:
    1) connexons
    2) Connexin (6 = 1 connexon)
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11
Q

Basal infoldings

A

Increases surface area for basal domains

Allows more transport of ions and proteins to be present and active transport of molecules

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12
Q

Lateral Digitations

A

Increases cell surface

Fluid and electrolyte transport

Found in gallbladder

Utilizes Na+/K+ atpase

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13
Q

Focal Adhesions

A

Anchors actin cytoskeleton to extracellular matrix

Detects and transduces signals from outside the cell

  • Contains transmembrane proteins:
    1) integrins

-Involved in cell migration

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14
Q

Simple Squamous

A

Flat

Lubrication, exchange barrier

Where:

  • Lining of the heart
  • Respiratory tracts
  • Lining of body caveties
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15
Q

Simple cubodial

A

Cube

Absorption, barrier, secretion

Where:

  • Kidneys
  • Hepatocytes
  • Thyroid
  • Ovary
  • Exocrine
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16
Q

Simple Columnar

A

Columns

Absorption, secretion

Where:

  • Gall bladder
  • Small intestines
  • Large intestines
  • Uterine tract
  • Stomach
17
Q

Pseudostratafied

A

Varies in size

Conduit, absorption, Secretion

Where:

  • Trachea
  • Male reproductive tract
18
Q

Stratified squamous

A

2t flat cells stocked in a superficial layer

Barrier, protection

Where:

  • Epidermis
  • Vagina
  • Oral cavity
  • Esophagus
19
Q

Stratified Cubodial

A

2t column cells

Barrier, conduit

Where:

  • sweat glands
  • Large exocrine glands
  • Anerectile junction
20
Q

Stratified columnar

A

Column cells

Barrier, conduit

Where:

  • Larger exocrine glands
  • Anerectile junctions
21
Q

Transitional

A

-Varies, dispensible

Barrier

Urinary tract

22
Q

Hemidesmosomes

A
  • Anchor connective tissue to basement membrane

- Has squiggly lines in them called INTEGRINS that helps anchor

23
Q

Bullous Pephigoid

A

Blister formation epithelium attachment to basement membrane

24
Q

Types of endocrine

A

-Release into connective tissues

1) paracrine-near by cells
2) autocrine- directly in same cell

25
Q

Difference between serous and muscosal cells

A

Serous:

  • Water
  • Darker staining
  • Nuclei round and oval

Muscosal:

  • Slimy
  • White staining

USE PAS: Has glucose

26
Q

Types of mixed glands

A

-Contains both serous and muscosal glands

Types:

1) Sublingual: Mucous > Serous
2) Submandibular: serous > mucous

Exam 1 FTM (22 decks)

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