lecture 8 : clinical neuropsyc assesment part 2 Flashcards

1
Q

JD case study
-what happened to him
-why was he referred
-treatment

A

-aged 54
-18 years of education
- Severe closed-head injury from car accident
- Frontal and temporal lobe damage

Reported issues (referred to neuropsycholgist)
-Mild speech and motor problems
-Unable to return to work
-Difficulties with multitasking, time management, memory, social interactions.

Neuropsychological testing revealed :
-Problems attention & executive function (control functions of cognitions (ability to switch task to task, inhibit irrelevent info)

Intensive rehabilitation resulted in improvements in executive function, time management and functional ability

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2
Q

assessing current cognitive functioning (what are the 3 important aspects in psyc)

A

a) intelligence
b) memory
c) language

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3
Q

classes of cognitive assessment

A

sensory reception and perception
-memory
-thinking and decision making
-motor functions
-language
-numerical processing
-executive function and attention

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4
Q

intelligence tests
-why is this test helpful

A

eg
wechsler adult intelligence scale (WAIS)
-within the wais it will pick up many classes of cognitive assessment
-

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5
Q

WAIS

A

Ten core subtests with mean of 10 and a SD of 3
The subtests are arranged into four indexes (mean 100, SD = 15)
There is also an overall IQ (Full Scale IQ) that is obtained by summing scores on all the subtests

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6
Q

clinical assesment with the WAIS
-why use it initially
-weaknesses

A

Use intelligence test as initial screening assessment (trying to identify is there a problem around this area)

-To help decide which areas to explore in more detail
-Standardised tests with observation
-May use shortened version involving fewer subtests
-Gives overall FSIQ and index scores
-Extensive standardization, excellent norms, good reliability and construct validity

Weaknesses of WAIS
-Does not assess executive functions
since they dont assess the specific skills that are needed in every day life :
-Predictive validity (the WAIS does not predict your ability to function in every day life )and treatment validity poorer than other tests

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7
Q

memory classes and problems

A

-short term memory (could asses digit span)
-working memory (storing and processing information)

-long term memory ;

(anterograde(post brain injury) retrograde (before the brain injury)) (crucial aspect of brain illness is separating these)

(verbal v non verbal)

(semantic v episodic) can get amnesia in these

procedural or implicit memory (memory without conscious recall)

prospective memory: remembering to carry out intentions etc taking meds

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8
Q

Wechsler memory scales (WMS)
-mean
-subtests
-evaluation

A

Mean = 100, SD = 15: co-normed with WAIS

Multiple subtests assess:
-Auditory-verbal immediate & delayed memory
-Visual-spatial immediate & delayed memory
-Working memory

Evaluation (see e.g. Kent, 2013)
-Good reliability
-WMS more sensitive to head injury than WAIS
-Does not assess procedural or prospective memory (can be important in every day function and helping design rehabilitation)
-WMS IV no assessment of verbal working memory
-Not linked to neuroanatomical theory of memory (how brain relates to memory, no theory to underscore the test design)
-Factor structure not as proposed in manual

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9
Q

assessing language
-aphasia
-what clinical examinations can be used

A

aphasia
-the set of different language impairments that you can get if you have brain illness

clinical examinations
-Spontaneous speech and observation
-To diagnose presence of aphasia

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10
Q

assesing language
after clinical exams : then diagnostic tests (understand nature of problem)

A

-E.g. Boston Diagnostic Aphasia Exam (BDAE III)

-To pinpoint nature of language problems (aphasia)
-To provide guidance for rehabilitation
-8 subscales: fluency, auditory comprehension, naming, oral reading repetition, automatic speech, reading comprehension, writing.
-
Very wide range of tasks (34 subtests!)
- Includes structured interview, observation and tests

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11
Q

Boston Diagnostic Aphasia Exam (BDAE )
evaluation

A
  • Time-consuming, requires specialist training

-Norms for aphasic patients, and small normal sample

-Reliability acceptable, lower for ‘qualitative’ scales

-Construct validity, diagnostic validity and treatment validity good
-e.g. Fong, Van Patten & Fucetola (2019): Factor analysis in 355 people with aphasia confirmed factor structure of the BDAE III

  • But only valid for those with relevant education and language exposure
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12
Q

Assessing executive function
-what is it

A

self regulation processes
- control/regulation of behaviour, cognition, planning, ability to switch

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13
Q

executive function preditcs….
struchen 2008

A

-Predict functional outcomes better than other cognitive variables
-Ecological validity important

Struchen et al. (2008)
121 people with brain injury
EFs predicted:
Return to work, social integration, marital success, and caregiver burden
Better than other measures of cognitive or physical functioning

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14
Q

Executive function measures predict return to work in a bipolar sample Drakopoulos et al. (2020)

A

Bipolar disorder associated with high levels of unemployment

120 patients with bipolar disorder

Looked at predictors of occupational status

demographic factors, clinical characteristics, IQ and executive function

Executive functioning was a more powerful predictor of occupational status than IQ, demographics and clinical factors, including illness severity.

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15
Q

types of executive function
-planning
-initiation , monitoring and control
-socioemotional control

A

planning
-decide goals, execute and adapt plans
-eg shopping, cooking,many work tasks

initiation, monitoring and control
-inhibition and switching, apathy
eg driving, self care, working

socioemotional control
-regulating mood and social behaviour
-eg social interactions, maintaining relationships, working

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16
Q

how can we measure executive function

A

neuropsychological tests
-eg fluency, Wisconsin card sort test, tower of London , Stroop

structured interviews
-dysexecutive function questionnaire

rating scales
-dysexecutive questionnaire

behavioural assessments
-multiple errands test

17
Q

what are the issues in assesing executive functions

A

traditional psychometrics may not apply
-EF tasks must be novel: test-retest reliability ?
-EF tasks must be unstructured : reliability lower?
-so if reliability is lower must be careful when interpreting scores

-ecological validity important
-naturalistic/complex settings : norms don’t apply
-instructions less directive

executive function tasks dissociated
-poor convergent validity (executive function tests dont correlate well with each other - or there are many aspects of executive function)

18
Q

EF test : tower tests (eg tower of london)

A

Instructions: Mentally plan sequence of moves to solve puzzle in fewest moves possible, then execute the plan

19
Q

evaluation of tower tests

A

Not well standardised
-No commercial version with good norms

Test-retest & split-half reliability adequate
-(> 0.7)

Good evidence of validity:
-Sensitive to brain damage
-Masson et al. (2010): correlates with measures of functioning and real world planning

Suitable for use in children and adults
-Participants find task enjoyable

20
Q

Test 2: Dysexecutive questionnaire (DEX)
Self-ratings and informant-ratings
evaluation

A

can be done as interview or self rating q
quite often patient rates themself then an informant will give a rating

20 item questionnaire
-Control of emotion, behaviour and cognition
-E.g. “I act without thinking, doing the first thing that comes to mind”

Evaluation (Shaw et al., 2015)
-Useful to have informant- and self- ratings, though poor inter-rater reliability (but then people with brain illnes tend to be unaware of their issues)
-Internal consistency >.8
-Concurrent validity with EF tests usually poor
-DEX self-ratings correlate with mood and quality of life assessments (someone who is depressed may have worse executive function)

Ratings limited: need objective tests too

21
Q

Test 3: Multiple Errands Test (MET)
Test with behavioural observation

A

real life test
Shopping/work errands task, and asked to carry them out
-Requires planning, self-initiation, monitoring

Can have standard structure
-But adapt to situation & surroundings
-Naturalistic form of functional assessment
-Observation of behaviour including social interactions, problem-solving, planning (someone actually also looks at how you carry it out)

22
Q

example of multiple errands test in
-control patient
-patient with frontal lobe damage

A

-the patient with dysexecutive syndrome with frontal lobe damage,you can see they take more routes, less efficient
-visited shops twice
-went backwards/forwards
-broke rules and went to area they weren’t meant to during task

-the control participant has a more efficient route

23
Q

evaluation of MET
-strengths
-weaknesses

A

Strengths:
-Observe behaviours and social interactions
-Assess behaviour in naturalistic setting
-Help design rehabilitation

-Cuberos-Urbano et al. (2013) :
Evidence of adequate inter-rater reliability
Predicts functional outcome: adaptive behaviour

Weaknesses:
Lack of control and standardisation: no norms -unexpected things happen when you do things in every day life , they wont always preditc every day outcomes as well
Not assessing specific functions in detail
Unexpected events