Lecture 8- bone growth and pathology Flashcards
Ossification
natural process of cartilage being transformed into bone.
Oss means
something to do with bone production
Diaphysis
shaft of the bone. Primary centre of ossification.
Epiphysis
end of bones. Secondary centre of ossification.
What happens when length of bones increase,
extremities or epiphysis of bones form.
Epiphyseal plates
growth plates formed of cartilage
Moulding
Bone growth in width
Endosteum
Inside of shaft of long bone
Medullary cavity
Central cavity within endosteum that store red/yellow bone marrow
Bone patholgy
When one of the main classes of cells overtakes another. = an imbalance of osteoclast and osteoblast activity
Osteoporosis
When bone degrades at a faster rate than it can be replaced. Makes bone more porous (holey).
Porous (holey) bone leads to
vulnerability to fractures. Loss of bone volume= less cancellous bone= more likely to collapse
Compressive forces on porous bone have ability to
fracture vertebrae and collapse it.
Oestrogen is important for…
bone production.
Causes of osteoperosis
Ageing, lack of exercise, bone mass and nutritional factors.
