LECTURE 10- Active cellular physiology Flashcards

1
Q

Shape of a cell is defined by…

A

how cell manages water, ions and solutes in the body.

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2
Q

Concentration gradient can depend on…

A

water and its solute. eg sugar in solution moving from high conc. of solute to a low conc. as solute dissolves. (diffusion)

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3
Q

Osmosis

A

Water moves through a semi-permeable membrane from an area of high conc. to an area of low conc. (passive transport)/

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4
Q

Which form of transport is used for the movement of a solute between membranes?

A

Osmosis. Membrane is permeable to water. However holes are too small for solute to move through. Water molecules move from high conc side of water to low conc side of water. Water attempts to dilute solute.

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5
Q

What happens when water moves across a membrane?

A

The volume of water on the side that the water molecules move to will increase, and decrease on opposite side.

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6
Q

What is osmotic pressure (tonicity)?

A

Applying pressure to an area of water that will counteract its change in volume and will make volume on either side of the membrane equal.

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7
Q

Purpose of osmotic pressure?

A

Maintains plump, strong but soft cells in lining of organs.

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8
Q

Water can be taken in/ and lost by…

A

drinking water. Lost through skin, sweat, lungs , faeces etc. Moves through ICF and ECF.

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9
Q

Where are solutes and ions found ?

A

In ICF and ECF.

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10
Q

What does isotonic mean? (iso= same)

A

Solutes within ICF and ECF are at same concentrations for a given volume. It is balanced

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11
Q

What does hypertonic mean? (hyper= more than)

A

When water is lost in ECF, but concentration of this solute remains the same just in a smaller volume.

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12
Q

How do we reach equilibrium in an hypertonic situation?

A

Water from ICF moves across to the ECF to compensate loss of water in ECF, and restore osmotic equilibrium. Consequence= total volume within cell decreases= so cell shrinks.

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13
Q

What does hypotonic mean? (hypo=

A

If volume of water increase, this water will flow from area of low conc of solutes and increase volume of water in this space.

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14
Q

Shape of cell in isotonic solution..

A

Maintains its shape.

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15
Q

Shape of cell in hypertonic solution…

A

Cell shrinks as water is lost.

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16
Q

Shape of cell in hypotonic solution…

A

Cell expands as water moves into cell.

17
Q

Ions are absorbed through which organs?

A

Epithelial lining of small intestine and colon (large intestine.

18
Q

Skeleton, body fluids, sweat glands and kidneys contain…

A

ions. ( ICF and ECF). Ion levels must be balanced

19
Q

What are excitable tissues?

A

In neurons and muscles- excitable membrane potential.

20
Q

Do epithelial cells have an excitable membrane?

A

No. They only have a membrane potential.

21
Q

Which ions do the cellular membrane potential rely on?

A

Na+ and K+. Important for health of excitable cells.

22
Q

Cations and anions of cell are found…

A

inside and outside of cell. Inside cell, across plasma membrane there is a slight negative over positive side.

23
Q

What acts as an insulator in the plasma membrane?

A

The lipid bilayer. Channels are formed in this to allow ions to pass between cells. Prevents free flow.

24
Q

Which ions are used like a small battery in cell?

A

Charge difference between two sides of membrane. High Na+ and low K+ on ECF outside ( think of sweat). Na+ low on ICF inside and K+ high.

25
Q

What is the resting membrane potential?

A

Distribution of ionic concentration that generate resting membrane potential. Have to be maintained for ‘battery’ to maintain.

26
Q

Ion channel or pore…

A

Channel for ions to pass between ICF and ECF. Ions DO NOT PASS THROUGH PLASMA MEMBRANE. Can only move when channels are open. They move to where their low conc would be.