Lecture 7 - Microbial interactions and antibiotic resistance

Question 1

What is an antibiotic?

Answer 1

Compounds used to kill or inhibit the growth of bacteria

Question 2

Mechanisms of resistance

Answer 2

• Enzymes
• Efflux pumps
• Changes in cell membrane
• Changes in cell targets

Question 3

Resistance is an evolutionary problem

Answer 3

Resistant and sensitive bacteria, sensitive bacteria die, resistant bacteria dominate

Question 4

Minimum Inhibitory concentration

Answer 4

The minimum concentration of antibiotic required to completely inhibit growth

Question 5

Minimum Selective concentration

Answer 5

The minimum concentration of antibiotic that provides a growth advantage to resistance strains