Lecture 10 - Bioinformatics of microbial communities Flashcards
1
Q
Human microbiome
A
All microorganisms living on and within the human body
2
Q
Cystic fibrosis microbiome
A
Thicker mucus - chronic colonisation, triggers an exacerbation and impaired lung function
3
Q
Exacerbation: what is it and what drives it in cystic fibrosis?
A
a sudden worsening of respiratory symptoms that requires medical attention
- Presence of certain types of bacteria (?)
4
Q
Sputum
A
Coughed up material originating from the lungs
5
Q
How may we sequence bacteria?
A
16sRNA sequencing - a type of RNA present in all bacteria that can be amplified and sequenced
Culture plates and then do 16sRNA sequencing
6
Q
OTUs
A
Operational taxonomical units
Different species
7
Q
MAGs
A
Metagenome assembled genome
