lecture 7

Question 1

consituents of endomembrane system

Answer 1

nuclear envelope
rough ER
smooth ER
golgi
vesicles
plasma membrane

Question 2

functions of smooth ER

Answer 2

1. metabolism of carbohydrates
2. lipid synthesis for membranes
3. detoxification of drugs and toxins
4. storage of Ca2+

Question 3

functions of rough ER

Answer 3

1. synthesis of membrane bound proteins

2. proteins enter lumen interior of rER

Question 4

functions of the golgi

Answer 4

1. glycosylation of proteins
2. addition and modification of proteins
3. sorting proteins to vesicles
4. directing vesicle trafficking
5. retrieval tags (integrity and function)
6. other tags (secretory pathways)

Question 5

exocytosis pathways

Answer 5

constitutive: release proteins that make ECM
regulatory: release hormones and neurotransmitters

Question 6

endocytosis tyeps

Answer 6

phagocytosis- phagocytotic vacuole digested
pinocytosis non selective uptake of solutes
receptor-mediated collects concs specific molecules e.g Low density lipis (LDLs)

Question 7

lysosome function (contain hydrolytic enzymes-acidic)

Answer 7

digest endocytosed materials
degrade proteins lipids carbs nucleic acids
digest cellular materials
digest unwanted intracellular structures
important for cell health
cell destruction autophagy cell death