Lecture 7 Flashcards
regions of the gene that are coded
Exons
Non coding regions of the gene
introns
alternate form of a gene
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Allele
Pathogenicity
Property of causing disease
Genes that are absolutly required to cause disease. aka the genes that make an organism a pathogen
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Pathogenicity genes
Genes that are associated with degree of virulence/agressivness on host. eg genes that help pathogens to spread faster, more capable of causing disease
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Virulence genes/virulence factors
what happens when there is a disruption of pathogenicity genes
complete loss of disease/significant reduction in disease in plants
How is the variability in sexually reproducing organisms
all progeny (decendents) are variable
How is the variability in asexually reproducing pathogens
reduced degree/intensity and frequenct of variability among decendents. But the quantity is great meaning a low frequency of variablity could still be quite significant
What causes variability in plant pathogens
12 kinds & spelling
- Mutation
- sexual recombination
- Gene & genotype flow
- genetic drift
- selection
- life cycle
- pathogen fitness
- heterokaryosis
- parasexuality
- vegetative incompatibility
- heteroploidy
- sexual-like processes in bacteria (conjugation, transformation, transduction)
what do you call a loss of pathogen virulence in culture (spelling)
attenuation
Further classification based on what host the pathogen attacks
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- ” special forms” (formae speciales)
- “Varirties”
Further classifications of special forms
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- races
- pathotypes
further classifications of race & pathotypes
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- isolates
each individual spore in an isolate
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- biotype
How do plants defend themselves agasint pathogen attack
5 main ways & spelling
- non-host resistance
- basal defence (preformed structureal & chemical defense)
- induced structureal defence
- induced biochemical defence
- detoxification of plant pathogen toxins
- other mechanisms
What are the types of mutations
5 & spell them
- Signle nucleotide polymorphism (SNP)
- structural variations (insertion/deletion)
- frameshift mutation
- excision of transposable elements (TEs)
- complete loss of an allele/gene (rare)
Mutations
- sudden Heritable changes in the genetic material
- most mutations are recessive in nature there fore diploid/dikaryotic individuals can not expressed the mutations until they are brought together in a homozygous state
Mutation at a locus/allele that codes for an enzyme could produce a different allele that produces different enzyme
spelling
allozyme
Gene flow vs genotype flow
Gene flow:
- certain alleles (genes) move from one geographically separated population to another.
- lower in soil-borne fungi & nematodes
- Population 1 x popluation 2 -> making new population 3
Genotype flow:
- completel genotypes move into a new population. a feature of clonally/asxually reproducing pathogens
- Population 1 moving into population 2
increased population size & higher genetic diversity
Gene flow
lower genetic diversity but may increase diversity among populations
selection
Genotype flow example (like the name of the pathogen)
- rust
- mildew
Genetic drift
- random fluctuations in frequency of alleles in a population due to random sampling (in smaller populations)