lecture 7 Flashcards
what is the endocrine system
glands located all throughout the body that secrete various hormones into the blood stream
hormones produced are secreted to help maintain what
homeostasis
the hormones produced by the endocrine system maintain what things in the body
-fluid balance
-metabolism, energy balance
-contraction of smooth and cardiac muscle
-growth and development
-reproduction
-circadian rhythms
hormones flow through ________
capillaries
what system is used when hormones are needed through out the body
lock & key
the hormones are the ____ in the lock and key system
key
the target cells or receptor sites are the _____ in the lock and key system
lock
receptor site is ______ for one hormone
specific
what is the most common type of endocrine feedback system
negative feedback system/mechanism
what does the negative feedback system/mechanism do
reverse changes that occured in the controlled condition
the negative feedback system will result in the gland increasing or decreasing the _____ of a hormone
release
Hormone secretion usually depends on the body’s need for the final action of the hormone
- Body condition moves away from normal range
- Specific hormone stimulated -> starts chain of events to return body to normal
- Once need is met and body condition normalized, secretion of the hormone will cease
glands of the endocrine system (10)
-pineal gland
-hypothalamus
-anterior and posterior pituitary gland
-thyroid gland
-parathyroid gland
-thymus
-adrenal glands (2)
-pancreas
-ovaries
-testes
what produces regulatory hormones that are either releasing hormones or inhibiting hormones
hypothalamus
what is the function of regulatory hormones
to stimulate or inhibit release of hormones from the anterior pituitary gland
the hypothalamus is responsible for synthesizing what hormones
oxytocin and antidiuretic hormone (ADH)
oxytocin and antidiuretic hormone are made by the hypothalamus but stored and released from where?
the posterior pituitary gland
This is regulated by the hypothalamus by inhibiting or releasing hormones
anterior pituitary gland
the anterior pituitary gland contains ______ hormones
tropic
hormones that send messages to other endocrine glands to release their hormones are called
tropic hormones
what are the 4 tropic hormones
-thyroid stimulating hormone
-adrenocorticotropic hormone
-follicle-stimulating hormone
-luteinizing hormone
what are the other two hormones in the anterior pituitary gland that act directly on final target tissues
-growth hormone
-prolactin
TSH sends messages to what gland to release their hormones
thyroid
ACTH sends messages to what gland to release their hormones
adrenal glands
FSH sends messages to what gland to release their hormones
ovary/testes
LH sends messages to what gland to release their hormones
ovary/testes
the growth hormone affects what
body tissues
prolactin affects what
mammary gland
what is the extension of the hypothalamus that does NOT synthesize hormones
posterior pituitary gland
where are the hormones produced that are in the posterior pituitary gland
the hypothalamus
the posterior pituitary gland stores and releases what hormones
antidiuretic hormone and oxytocin
antidiuretic is also known as what
vasopressin
what is the mnemonic for the hormones of the anterior pituitary gland
flat pig -fsh, lh, acth, tsh, prolactin, ignore, gh
what is the target organ and effects for thyroid stimulating hormone (TSH)
-thyroid gland
-stimulates thyroid gland to secrete thyroid hormones
what is the target organ and effects for adrenocorticotropic hormone (ACTH)
-adrenal gland (cortex)
-stimulates adrenal cortex to secrete glucocorticoids (cortisol)
what is the target organ and effects for follicle-stimulating hormone (FSH)
-ovary and testes
-stimulates secretion of estrogen and the development of ova in women and sperm development in men (control of reproductive function)
what is the target organ and effects for luteinizing hormone (LH)
-ovaries and testes
-stimulates ovulation in women and secretion of sex hormones in both men and women (control of reproductive function)
what is the target organ and effects for growth hormone (GH)
-liver, adipose tissue
-promotes growth (indirectly)
what is the target organ and effects for prolactin
-mammary gland
-stimulates breast development necessary for lactation after child birth
what is the target organ and effects for antidiuretic hormone or vasopressin
-kidney
-regulates fluid volume by stimulating reabsorption of water in the kidneys
what is the target organ and effects for oxytocin
-ovary and testis
-stimulates ejection of milk into mammary ducts and uterine contractions
what gland is anterior to the trachea and consists of two lobes
thyroid gland
what three hormones are produced by the thyroid gland
-triiodothyronine T3
-thyroxine T4
-calcitonin
what is the only gland of the endocrine system that can be palpated
thyroid gland
why must a provider take precaution when palpating the thyroid
because it can release additional hormones and exacerbate symptoms
thyroid hormones are essential for what things
-physical growth
-mental development
-reproductive maturation
-metabolic activity
-life
thyroid hormones increase the metabolic rate of the body utilizing ______ and producing ______
-energy
-heat
if a person is in cold temps will more or less thyroid hormones be released to increase heat production
more
in order for the body to produce T3 and T4 there must be a sufficient intake of what two things
-protein
-iodine
calcitonin is release when serum calcium levels are too _____
high
calcitonin inhibits breaking down bones for calcium and phosphate which does what
-keeps calcium from leaving the bones
-decreases resorption of calcium in the kidneys
calcitonin ____ serum levels of calcium
lowers
how can a nurse assist with palpation of the thyroid
-position them
-giving patients sips of water
what are the four glands that sit on the thyroid gland
parathyroid gland
what does the parathyroid gland produce
parathyroid hormone
parathyroid hormone raises serum _____ levels and _____ levels
-calcium
-phosphate
the parathyroid hormones ____ calcium that is stored in bones
pulls
the parathyroid hormones encourages the _____ and ______ to reabsorb more calcium
kidneys and small intestine
the target organs of the parathyroid hormone include what organs
-bones
-small intestine
-kidneys
where does the adrenal glands sit
on top of the kidneys
the adrenal glands consist of what two sections
-adrenal medulla
-adrenal cortex
what hormones does the adrenal medulla release
epinephrine and norepinephrine
when epinephrine and norepinephrine are released from the adrenal medulla these catecholamines act as ______ not ______
-hormones
-neurotransmitters
hormones from the adrenal medulla are released during what
stress to manage the bodys stress response
the release of epinephrine and norepinephrine from the adrenal medulla causes what SNS response
-increased cardiac contractions
-increased cardiac output
-increased heartrate
-increased BP
-bronchodilation
-enhanced blood flow to muscles
-increased glucose availability
what are the three hormones produced and secreted from the adrenal cortex
-mineralocorticoids (aldosterone)
-glucocorticoids (cortisol)
-gonadocorticoids (androgens)
what do mineralocorticoids (aldosterone) do in the body
-acts on kidneys to conserve sodium and fluid follows
-acts on kidneys to rid the body of potassium
-increased serum sodium, decreased serum potassium, increased fluid volume, increased blood pressure
what do glucocorticoids (cortisol) do in the body
-provides energy sources to the body and ensures glucose is made available for the brain
-acts on liver to convert glycogen to glucose
-released during body’s response to stress - the body requires more energy for stress induced changes
when the body is stressed, the ______ tells the ________ gland to release ACTH, then travels to the adrenal cortex and stimulates release of cortisol
-hypothalamus
-anterior pituitary gland
what do gonadocorticoids (adrogens) do in the body
contribute to libido and reproduction
if a person has hyperkalemia ______ will be released to lower potassium
aldosterone
adrenal cortex mnemonic
Make Good Sweets
saying: salt, sex, sugar
Mineralocorticoids, Glucocorticoids, Sex hormone
mnemonic for adrenal medulla
-men
Medulla
Epinephrine
Norepinephrine
what is both an endocrine and exocrine gland
the pancreas
what is the function of the pancreas as an exocrine gland
release of amylase and lipase for digestion assistance
what is the function of the pancreas as an endocrine gland
secretes insulin and glucagon for glucose homeostasis into the blood stream
cells within the pancreas includes:
alpha and beta cells
what do alpha cells secrete
glucagon
what do beta cells secrete
insulin
alpha and beta cells live within a section of the pancreas called what
islet of langerhans
this is released by the pancreas when serum glucose rise
insulin
Insulin is the ___ to unlock the cells
key
once cells are unlocked ______ can travel inside the cells and be used for energy
glucose
without insulin the cells will starve because they cannot what
metabolize glucose
this is released by the pancreas when serum glucose levels are low
glucagon
glucagon stimulates the liver to turn glycogen to ______
glucose
______ is imperative to combat hypoglycemia because it can lead to brain death
glucagon
causes of endocrine disorders
-overproduction of the hormone
-underproduction of the hormone
-side effects of certain drugs
a primary endocrine disorder means something is wrong with what
the gland itself
a secondary endocrine disorder means something is wrong with what
a different gland/organ affects the endocrine gland
what decreases in the endocrine system as we age
-growth hormone
-decrease in tsh and thyroid hormone
-insulin secretion
as you age and there is a decrease in growth hormone this happens to the body
decrease in muscle mass and increase in fat storage
as you age and there is a decrease in TSH and thyroid hormones this happens to the body
decrease in basal metabolic rate
as you age and there is a decrease in insulin secretion this happens to the body
decrease in glucose tolerance but not diabetes
as we age and the endocrine system functions decrease is causes a decrease in _____
energy
disorder of carbohydrate metabolism
diabetes mellitus
the body is intolerant to glucose for what reasons
-the pancreas has developed faulty production of insulin either decreasing it or ceased completely
-the tissues have become insensitive to the insulin
how is an individual diagnosed with diabetes
various ways but an elevated HbA1C is most common
type 1 dm accounts for what percent of all diabetes mellitus
5%