Lecture 6 - thrombocytopenia

Question 1

1-3. three causes of thrombocytopenia

Answer 1

1. dec production
2. ↓ survival
3. ^abnormal sequestration

Question 2

1. what platelet level to get lots of bleeding with trauma?

lots without trauma?

Answer 2

1. < 40,000

< 10,000

Question 3

1-3. What are some infectious caues of thrombocytopenia?

Answer 3

1. Type II BVDV, EIA, anaplasma

Question 4

1. what drugs are given to combact immune mediated thrombocytopenia?

Answer 4

1. dextamethasone and prednisolone

Question 5

(brackenfern toxicosis)

1. causes anemia in what animals?
2. toxic compounds do what?
3. more toxic: young or old plants?
4. more toxic: leaves or stems and roots?
5. mortality?
6. Short term (weeks) high level exposure –>
7. Long-term (months to years) low level exposure in ruminants –>
8. prognosis?

Answer 5

1. cattle + sheep (not horses – neurologic signs)
2. suppress bone marrow (pancytopenia)
3. young
4. stems and roots
5. high
6. severe aplastic anemia
7. hemorrhagic cystitis and bleeding bladder tumors (enzootic hematuria)
8. HOPELESS

Question 6

1. what is the most common form of anemia in horses?

Answer 6

1. depression anemias

Question 7

(Anemia of Inflammatory Diseases)

1. protection by reducing what?

so what does this mean?

(Anemia secondary to renal/hepatic failure)

2. interference with what?

Answer 7

1. Fe (so bacteria can’t use)

Fe suppementation doesn’t work

2. Epo prod