lecture 3

Question 1

1-4. four causes of heinz body anemia (oxidation)?

Answer 1

1. red maples leaves
2. onion
3. brassica
4. phenothiazine dewormers

Question 2

1. how is copper toxic?
2. see what w/ acute ingestion?
3. if parenteral?
4. where is copper stored in chronic cases?

what causes release?

5. how can you check for increased copper before toxic event?

Answer 2

1. protein coagulants
2. irritation + necrosis of GI, kidney, liver, and fatal shock.
3. no GI signs
4. liver

hepatic injury, stress, or starvation

5. liver biopsy

Question 3

1. what does parenteral mean?

Answer 3

1. not delivered through the GI tract

Question 4

(copper toxicity)

1. what chelator is used?
2. what used to enchance fecal excretion?
3. what protects RBC from effects of copper?

Answer 4

1. D-penicillamine
2. oral sodium thiosulfate, ammonium, sodium molybdate
3. IV sodium tetrathiomolybdate

Question 5

1. what effect does ^molybdenum have on copper absorption?
2. what causes 2° copper toxicity?

Answer 5

1. decreases it
2. molybdenum deficientcy

hepatotoxic plants

Question 6

(Equine Babesiosis)

1. tick borne - what kind?
2. what two bacteria strains cause?
3. do cows get it?
4. what happens to survivors?
5. how do you diagnose?
6. tx of choice?

Answer 6

1. Dermacentor Nitens
2. B. caballi (NA), T. Equi (europe)
3. no - its been eradicated
4. become asymptomatic carriers for life
5. Cx, parasites in RBC (early), ELISA (seroconversion after 14 days)
6. imidocarb

Question 7

(water intoxication)

1. what age gets?
2. leads to what?
3. how severe?
4. tx?

Answer 7

1. young calves when given free access to cold drinking water
2. osmostic lysis of RBC
3. severe anemia is rare
4. take away water… restore blood osmolarity (IV saline)