Lecture 6 Learning Objectives Flashcards

1
Q

Singer and Nicholson model of plasma membrane

A

Fluid mosaic model

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2
Q

Phospholipids in outer leaflet

A
Cholesterol
Glycolipids
Sphingomyelin 
Phosphatidyl Choline
Glycosylphosphatidyl inositol
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3
Q

Phospholipids in Inner leaflet

A

Cholesterol
Phosphatidyl inositol
Phosphatidyl ethanolamine
Phosphatidyl serine (negative charge)

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4
Q

Where are glycolipids located in the plasma membrane

A

Only on outer leaflet

Imparts antigenicity to cell

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5
Q

Lipid Raft Functions

A
Compartmentalize cellular processes 
Assembly of signal molecules
Influence membrane fluidity 
Membrane protein trafficking 
Regulates neurotransmission and receptor traffic
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6
Q

Glycocalyx

A

Not integral part of membrane
Carb coat on extracellular cell surface composed to glycolipids and glycoproteins
Protects cell from ionic, mechanical stress
Barrier
Cell-to-cell communication

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7
Q

Peripheral proteins

A

Found on inner and outer leaflet - can be more easily removed than integral proteins

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8
Q

Integral proteins

A

Embedded within phospholipid bilayer - associate with the nonpolar core of the bilayer

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9
Q

Transmembrane

A

Integral proteins that pass completely through the bilayer - channel or transporter proteins

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10
Q

Passive transport

A

No energy required - may require transport molecules

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11
Q

Diffusion

A

Type of passive transport - movement of ions or molecules from high to low concentrations - no transport molecule needed

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12
Q

Osmosis

A

Diffusion of solvents across cell membranes - no transport molecule needed

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13
Q

Facilitated diffusion

A

Diffusion using transporter molecule

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14
Q

Active transport

A

Movement against a concentration gradient- requires energy and transport molecule

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15
Q

Uniporters

A

Move one molecule in one direction

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16
Q

Symporters

A

Move two or more molecules in the same direction

17
Q

Anti porter

A

Move two or more molecules or ions in opposite directions