Lecture 6- Extracellular Structures Flashcards
plant cell wall function
maintains cell shape and prevents excess uptake of water
structure of plant cell wall
cellulose
animal extracellular matrix (ECM) function
maintains cell attachments across long distances, allows communication, maintains tissue integrity, stores growth factors
ECM structure
secreted glycoproteins
collagen
forms matrix of ECM and connects cells over long distances
fibronectin
link collagen to integrins
integrins
proteins that link ECM to the cytoskeleton
epithelial layers
layers of cells b/w you and environment
epithelial cells must stay connected to _____ and to _______ otherwise they undergo apoptosis
ECM; each other
tumor
mass of cells that arose from unregulated cell divisions and through accumulation of mutations
one major early steps in cancer progression is a _______to ECM
loss of attatchment
intercellular junctions in epithelial cells maintain _______
tissue integrity
tight junctions function
seal cells together and prevent passage of molecules in between gap between cells
desmosomes function
distribute stretching force across a tissue and connect the cytoskeleton (IF) of adjacent cells
gap junctions function
provide non-selective transport of small molecules b/w cells
-allows sharing nutrients and signals