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BIOL31571 > Lecture 6 - Congenital hyperinsulinism of infancy > Flashcards

Lecture 6 - Congenital hyperinsulinism of infancy Flashcards

1
Q

Patch clamp

A

Measures ion passage through a channel - we can know which ion channel our glass pipette is on

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2
Q

CHI

A

Channels porduced, trapped in cell, never make it to membrane

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3
Q

Transient

A

Temporary

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4
Q

Focal

A

One small section causing pathology

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5
Q

Diffuse

A

Large areas causing pathology - most has to be removed

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6
Q

Can a 100% pancreasectomy happen

A

No, some bits so tightly close to intestines you can’t remove it without damaging the intestines - bets you casn do is a 98% pancreatectomy

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7
Q

H19

A

regulates IGF2 - excessive IGF2, promoting beta cell hyperplasia

mRNA

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8
Q

p57^kip2

A

Controls cell cycle arrest - beta cell hyperplasia

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9
Q

18-F dopa

A

short half life, produces bright spot in overactive beta cells

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10
Q

Consanguineaous

A

Related - cousins, etc

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11
Q
A
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BIOL31571 (8 decks)

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