Lecture 6 Flashcards

1
Q

Define somatic sensation

A

Sensation from body tissues

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2
Q

Define somatic sensation

A

Sensation from body tissues

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3
Q

What does fibre Aalpha sense?

A

Motor and somatic proprioception

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4
Q

What do Abeta nerve fibres sense?

A

Touch pressure

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5
Q

What do Adelta nerve fibres sense?

A

Pain and temperature

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6
Q

What do Agamma nerve fibres sense?

A

Motor spindles

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7
Q

What do B nerves do?

A

they are pregangionic sympathetic neurons

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8
Q

What do C fibres sense?

A

Pain and they are the post-ganglionic sympathetic neurons

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9
Q

Which type of nerve fibre is responsible for touch pressure?

A

Abeta (II)

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10
Q

Which type of nerve fibre is responsible for motor and somatic proprioception?

A

A alpha (I)

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11
Q

Which type of nerve fibre is responsible for pain and temperature?

A

A delta (III)

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12
Q

Which type of nerve fibre is responsible for motor spindles?

A

A gamma

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13
Q

Which type of nerve fibre is pre-ganglionic sympathetic?

A

B

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14
Q

Which type of nerve fibre is responsible for pain and is post-ganglionic sympathetic?

A

C (IV)

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15
Q

Which type of nerve fibre is unmyelinated?

A

C

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16
Q

Why are there 2 sets of pain fibres?

A

A delta mediates sinal reflexes such as the withdrawal reflex
C nerves become more sensitive when the tissue is damaged

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17
Q

What neurons are involved in skin innervation?

A

Meissner’s corpuscle detects steady pressure
Bare nerve ending detects pain
Pacininian corpuscle detects vibration
Merkel’s receptor detects pressure

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18
Q

What is the threshold for cold pain and which nerve fibre detects it?

A
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19
Q

What is the threshold for hot pain and which nerve fibre detects it?

A

> 46C if held and type C

>52C would to reflexively pulling away and both type C and Adelta

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20
Q

Give an example of a rapidly adapting neuron

A

Pacinian corpuscle

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21
Q

Give an example of a slowly adapting corpuscle

A

Merkel Cell

22
Q

What do prostaglandins mediate?

A

Primary hyperalgesia

23
Q

List some common inflammatory mediators

A
Prostaglandins
Bradykinin
5-HT receptor
Histamine
Purines
Neuropeptides
24
Q

What are the main sources of inflammatory mediators?

A

Leukocytes

Mast cells release histamine

25
Q

What are the main sources of inflammatory mediators?

A

Leukocytes

Mast cells release histamine

26
Q

What does fibre Aalpha sense?

A

Motor and somatic proprioception

27
Q

What do Abeta nerve fibres sense?

A

Touch pressure

28
Q

What do Adelta nerve fibres sense?

A

Pain and temperature

29
Q

What do Agamma nerve fibres sense?

A

Motor spindles

30
Q

What do B nerves do?

A

they are pregangionic sympathetic neurons

31
Q

What do C fibres sense?

A

Pain and they are the post-ganglionic sympathetic neurons

32
Q

Which type of nerve fibre is responsible for touch pressure?

A

Abeta (II)

33
Q

Which type of nerve fibre is responsible for motor and somatic proprioception?

A

A alpha (I)

34
Q

Which type of nerve fibre is responsible for pain and temperature?

A

A delta (III)

35
Q

Which type of nerve fibre is responsible for motor spindles?

36
Q

Which type of nerve fibre is pre-ganglionic sympathetic?

37
Q

Which type of nerve fibre is responsible for pain and is post-ganglionic sympathetic?

38
Q

Which type of nerve fibre is unmyelinated?

39
Q

Why are there 2 sets of pain fibres?

A

A delta mediates sinal reflexes such as the withdrawal reflex
C nerves become more sensitive when the tissue is damaged

40
Q

What neurons are involved in skin innervation?

A

Meissner’s corpuscle detects steady pressure
Bare nerve ending detects pain
Pacininian corpuscle detects vibration
Merkel’s receptor detects pressure

41
Q

What is the threshold for cold pain and which nerve fibre detects it?

42
Q

What is the threshold for hot pain and which nerve fibre detects it?

A

> 46C if held and type C

>52C would to reflexively pulling away and both type C and Adelta

43
Q

Give an example of a rapidly adapting neuron

A

Pacinian corpuscle

44
Q

Give an example of a slowly adapting corpuscle

A

Merkel Cell

45
Q

What do prostaglandins mediate?

A

Primary hyperalgesia

46
Q

List some common inflammatory mediators

A
Prostaglandins
Bradykinin
5-HT receptor
Histamine
Purines
Neuropeptides
47
Q

Which receptors detect thermal pain?

A

TRPV1 - Aching

TRPV2 - Reflex

48
Q

What are the main sources of inflammatory mediators?

A

Leukocytes

Mast cells release histamine

49
Q

What are the two roles of prostaglandins?

A

Senstitisation e.g. PGE2

Excitation e.g. PGI2

50
Q

What are NSAIDs?

A

Non-steroidal anti-inflammatory drugs e.g. ibruprofen and voltarol which work by inhibiting Cox-1 and Cox-2

51
Q

What are the 5 spinal regions?

A
Cervical Region    8 segments
Thoracic Region    12 segments
Lumbar Region      5 segments
Sacral Region         5 segments
Coccygeal              3 segments