Lecture 5 (PMR)- Exam 2 Flashcards

1
Q

Emotional effects of serious illness or injury:
* What can disrupt all aspects of life?
* May develop how?
* Overwhelming waves of what?
* Emotional upheavel can make it what?
* Important to remember what?

A
  • Serious health problem can disrupt all aspects of life.
  • May develop unexpectedly.
  • Overwhelming waves of difficult emotions from fear and worry to profound sadness, despair to feelings that make it difficult to cope.
  • Emotional upheaval can make it difficult to function or think straight, can lead to mood disorders such as anxiety and depression.
  • Important to remember that no one is powerless.
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2
Q

Common emotional responses to serious illness:
* What happens as they struggle to come to terms with the diagnosis?
* Facing up to what?
* Worrying about what?

A
  • Anger or frustration as they struggle to come to terms with the diagnosis.
  • Facing up to one’s own mortality and the prospect that the illness could potentially be life-ending.
  • Worrying about the future, how will one cope, pay for treatment, what will happen to loved ones as they face the fact that the illness will progress.
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3
Q

Common emotional responses to serious illness:
* Grieving what?
* Feeling what?
* Sense of what?
* Experienceing what?

A
  • Grieving the loss of one’s own health and old life.
  • Feeling powerless, hopeless, or unable to look beyond the worst-case scenario.
  • Sense of isolation, feeling cut off from friends and loved ones who can’t understand what someone would be going through.
  • Experiencing a wide range of difficult emotions is a normal response.
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4
Q

Facing a serious diagnosis:
* What is the way to respond?
* Everyone needs time to what?
* Allow time to what?
* be patient with what?
* Be open to what?

A
  • There is no right or wrong way to respond.
  • Everyone needs time to process the news and be kind as they adjust to the new situation.
  • Allow time to feel.
  • Be patient with the pace of treatment and recovery.
  • Be open to change.
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5
Q

Strategies for coping with a serious illness: Reach out for support
* Chose what?
* Do worry about what?

A
  • Choose the support that’s right, choose who to confide in, lean on and amount of information you elect to share about the situation.
  • Don’t let worries about being a burden keep anyone from reaching out.
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6
Q

Strategies for coping with a serious illness: Reach out for support
* Look for support from what?
* Make what a priority?
* Join what?

A
  • Look for support from friends and loved ones who are good listeners.
  • Make face-time a priority.
  • Join a support group.
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7
Q

Strategies for coping with a serious illness:
* Explore what?
* Bottling up emotions may only increase what?

A
  • Explore your emotions, being honest about any negative emotions one may be experiencing won’t delay recovery in any way, it may have opposite effect.
  • Bottling up emotions may only increase stress levels; elevate the amount of pain and make one more susceptible to anxiety and depression.
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8
Q

Strategies for coping with a serious illness:
* What can lead to inappropritate outburst?
* When feelings are freed, what can happen?

A
  • Facing emotions instead of internalizing which can lead to inappropriate outburst.
  • When feelings are freed, different emotions quickly come and go, even the most painful and difficult feeling will rapidly subside.
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9
Q

Strategies for coping with a serious illness:
* Manage stress which can contribute to what?
* Talk to someone you _

A
  • Manage stress which can contribute to or exacerbate many different health problems including cardiovascular disease, high blood pressure, GI disorders, chronic pain and wound healing.
  • Talk to someone you trust.
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10
Q

Strategies for coping with a serious illness:
* Adopt what practice?
* Get enough what?
* Be as _ as possible?

A
  • Adopt a relaxation practice.
  • Get enough sleep.
  • Be as active as possible.
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11
Q

Strategies for coping with a serious illness:
* Pursue what?
* Pick up what?
* Learn what?
* get involved wher?
* Spend time where?

A
  • Pursue activities that bring meaning and joy.
  • Pick up a long-neglected hobby.
  • Learn something new.
  • Get involved inthe community.
  • Spend time in nature.
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12
Q

Strategies for coping with a serious illness:
* Deal with what?
* What is common among patients dealth with a serious illness

A
  • Deal with anxiety and depression.
  • Mood disorders like anxiety and depression are common among patients dealing with a serious illness, they can create a vicious circle.
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13
Q

Strategies for coping with a serious illness:
* What do you need to manage?
* Take care of who?
* Be smart about what? Why?

A
  • Manage debilitating symptoms such as pain.
  • Take care of yourself.
  • Be smart about caffeine, alcohol and nicotine. Alcohol can worsen both anxiety and depression symptoms.
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14
Q

What are way to help someone cope with a serious illness (4)?

A
  • Offer support.
  • Listen.
  • Become educated about the illness.
  • Stay connected.
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15
Q

The Healthcare Provider Patient
* As healthcare providers, we are accustomed to what?
* Shifting to the role of a patient often involves what?
* This shift can lead to a unique set of what?

A
  • As healthcare providers, we are accustomed to being the caregivers, the ones who have control, knowledge, and authority.
  • Shifting to the role of a patient often involves a loss of control, vulnerability, and the stark reality of our own mortality.
  • This shift can lead to a unique set of emotional and psychological challenges.
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16
Q

What are the challenges that HCP face as patients (general)?(5)

A
  • loss of control
  • hyperawareness
  • Role reversal discomfort
  • Fear of judfement
  • Diffulty letting go
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17
Q

Challenges Healthcare Providers Face as Patients
* How do providers feel like they lose control?
* How is the role reversal?

A
  • Loss of Control: Providers are used to making decisions and having control over medical situations. As patients, they may feel helpless, especially when relying on others for their care.
  • Role Reversal Discomfort: Shift from caregiver to patient can create discomfort, as it challenges their identity and professional role.
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18
Q

Challenges Healthcare Providers Face as Patients
* How does awareness change?

A

Hyperawareness: With extensive medical knowledge, healthcare providers often become hyperaware of potential complications, risks, and the nuances of their condition, which can lead to increased anxiety and fear.

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19
Q

Challenges Healthcare Providers Face as Patients
* What do they fear?
* Providers have a diffciculty of what?

A
  • Fear of Judgement: May be fear of being judged by colleagues or other healthcare professionals, especially if the illness or injury is related to something the provider believes they should have prevented or managed differently.
  • Difficulty Letting Go: Many healthcare providers struggle to let go and allow others to take the reins, which can interfere with their ability to relax and focus on recovery.
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20
Q

Strategies for Dealing with Trauma When Becoming a Patient
* How can one accept and acknowlegde?

A
  • Recognize the shift – accept being a patient is different than a provider, it’s okay to feel vulnerable and uncertain.
  • Allow yourself to be vulnerable – it’s okay to feel fear, anxiety, and uncertainty. Embracing these emotions, rather than suppressing them, can lead to healthier coping.
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21
Q

Strategies for Dealing with Trauma When Becoming a Patient
* How should one get support?

A

Seeking Professional Support:
* Therapy and counseling – engaging with a therapist who understands the unique challenges faced by healthcare providers can be invaluable.
* Peer support groups – connecting with other healthcare providers who have experienced similar situations can offer understandings and validation

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22
Q

Strategies for Dealing with Trauma When Becoming a Patient
* How should one maintain open communication?

A
  • With healthcare providers – be open with your care team about your concerns, fears, and preferences. Clear communication can help build trust and ensure that your needs are met.
  • With loved ones – sharing your feelings and fears with family and friends can provide emotional support. They can offer a different perspective and help you process your experiences.
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23
Q

Strategies for Dealing with Trauma When Becoming a Patient
* how should one redefine their identity and role?

A
  • Embrace the patient role – allow yourself to step back from the provider role and focus on your own recovery. Trust the healthcare team to do their job, just as you would for your patients.
  • Balance knowledge and trust – while your medical knowledge is an asset, try to balance it with trust in your caregivers. Letting go of the need to control every aspect can reduce stress.
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24
Q

Strategies for Dealing with Trauma When Becoming a Patient
* How should one reassess professional boundaries?

A
  • Avoid self-treatment – resist urge to manage your own care. This can lead to increased stress and potential errors. Let your care team guide your treatment.
  • Reflect on boundaries – use this experience as an opportunity to reassess how you manage your own patients, potentially leading to more empathy and understanding in your practice.
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25
Q

Strategies for Dealing with Trauma When Becoming a Patient
* how should one reflect on the experience?

A
  • Journaling – writing about your experiences can help process emotions and provide insights into how the experience might change your approach to patient care in the future.
  • Finding meaning – reflect on how this experience might influence your work positively. Many providers find that being a patient enhances their empathy and understanding their professional roles.
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26
Q

Strategies for Dealing with Trauma When Becoming a Patient
* How should one return to work?

A
  • Gradual reintegration – when returning to work, consider a phased approach if possible. This can help you adjust and avoid feeling overwhelmed.
  • Ongoing support – continue to seek support even after you’ve returned to work. The transition back to your professional role may bring up new emotions or challenges that need addressing.
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27
Q

Psychological Evaluation in Rehabilitation Settings
* Patients are forced to deal with what?
* Reality of changes with what?
* During acute phase, what can be a source of distress and irritation?

A
  • Patients are forced to deal withemotionssuch as powerlessness,shock, demoralization and loss while dealing with a variety ofphysical discomforts.
  • Reality of changes with lifestyle, relationships and financial changes.
  • During acute phase,physical and cognitive deficits as well as the inability to perform simple daily functions can be a source ofdistress and irritation.
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28
Q

What are all the common psychological reactions and disorders? (general)(6)

A
  • Adjustment disorders
  • Depression
  • Anxiety
  • Guilt
  • Denial of illness
  • Caregiver distress
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29
Q

Common Psychological Reactions and Disorders
* What are the adjustment disorders?
* What can occur? What can that lead to?

A
  • Psychological distress, physical disfigurement, reduced functional independence.
  • Significant emotionalreactions can occur that can lead to poor adjustment or lead todepression or anxiety.
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30
Q

Common Psychological Reactions and Disorders: Depression
* MC what?
* Can lead to waht?
* This has been linked to what?
* What are the risk factors?

A
  • Most common manifestation in a rehabilitation setting.
  • Can lead to diminished attention, memory, motor skills which can lead tobarriers to recovery.
  • This has been linked to excess disability, slow physical recovery and increased mortality.
  • Risk factors include previous psychiatric illness,functional limitations and social isolation.
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31
Q

Common Psychological Reactions and Disorders: Anxiety
* Among patients this is what?
* Reactions to disabling events are often marked by what?
* What can increase rates ofanxiety disorders including PTSD?

A
  • Among patients this is well documented in literature.
  • Reactions to disabling events are often marked by significant worry, tension and feelings of loss of control.
  • Confrontedwith inevitability of death for the first time, resulting inincreased rates ofanxiety disorders including PTSD.
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32
Q

Common Psychological Reactions and Disorders: Guilt
* Occurs when?
* What can it heighten?

A
  • Occurs when one imposes self-blame for his or her injury or disability.
  • Painful emotionwhich may result in heightened levels of depression.
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33
Q

Common Psychological Reactions and Disorders: Denial of illness
* What is it?
* What is a significant barrier to rehabilitation. May refuse what?

A
  • A psychological coping mechanism that may emerge following a threat to one’s identity and self-preservation.
  • A deficit of self-awareness is a significant barrier torehabilitation. May refuse to participate in therapies out of belief that they are unimpaired. May leave without approval.
34
Q

Common Psychological Reactions and Disorders: Caregiver distress
* Acquired injury affects the family system how?
* Changes inwhat?
* Can lead to what?

A
  • Acquired injury affects the family system in varying ways and degrees such as change of roles and family functioning.
  • Changes in perceived romantic relationships, sexual life and changing role from partner to caregiver.
  • Can lead to caregiver depression, anxiety, decreased life satisfaction.
35
Q

Psychological and NeuropsychologicalAssessment Techniques: Clinical interview
* Interview who?
* Gathering information on what?
* For the elderly, inquire about what?

A
  • Interview with both the patient and other family members if available.
  • Gathering information on patients’ development, education and vocationalhistory.
  • For the elderly, inquire about preinjury functioning and look for signs suggestiveof premorbid cognitive decline or dementing conditions which can lead to a barrier of recovery.
36
Q

Psychological and NeuropsychologicalAssessment Techniques: Psychological assessments
* Evaluate what? how? (2)

A

Evaluate emotional functioning by questionnaires and inventories.
* Such as The Hospital and Depression Scale
* The Stroke Scale

37
Q

Psychological and NeuropsychologicalAssessment Techniques: Neuropsychological assessment
* An assessment that offers what?

A

An assessment that offers an objective, valid, and reliable method for detecting and tracking brain impairment.
* Quality of Life after Brain Injury

38
Q

Psychological andNeuropsychologicalAssessment Techniques
* Goals of the Neuropsychological evaluation is generally what?
* Patient timeis at a what?

A
  • Goals of the Neuropsychological evaluation is generally limited in scope.
  • Patient time is at a premium and the provider must compete with other disciplines to complete their work.
39
Q

Psychological and Neuropsychological Assessment Techniques
* Focuses on concepts such as what? (5)

A
  • information on premorbid conditions
  • identification of cognitive deficits
  • guidance for post discharge care and outcomes
  • driving ability
  • vocationalfunctioning
40
Q

Psychological Interventions in Acute Rehabilitation
* Life altering changes that accompany the disability in those exhibiting emotional distress are critical to what?

A

Life altering changes that accompany the disability in those exhibiting emotional distress are critical to fostering healthy adjustment, boosting coping skills and improving mood.

41
Q

Psychological Interventions in Acute Rehabilitation
* Barriers can occur due to various causes can include what? (4)

A
  • as one competes for patient timewith clinicians from other disciplines
  • suboptimal session timebecause ofpatient fatigue or illness
  • reluctance from the patient to engage in owing to preexisting biases
  • may harborsuspicion or mistrust or regardtherapy as for the mentally ill
42
Q

Goals of Psychotherapy
* To relieve what?
* Major goal is to boost what?

A
  • To relieve distress, maximizing functioning and quality of life.
  • Major goal is toboost patients’coping resources and help them adapt and manage the new medical, physical, cognitive, and psychological challenges.
43
Q

Goals of Psychotherapy
* Goals can include some of the following? (5)

A
  • facilitation of acceptance
  • instillation of hope
  • overcoming frustration
  • relaxation and distractions
  • identification of social support
44
Q

Psychological Intervention Strategies
* usually involve both what?
* Treatment is influenced by what?

A
  • Usually involve both direct and problem focused.
  • Treatment is influenced by patient and institutional factors.
45
Q

Psychological Intervention Strategies
* Commonly used intervention strategiescan include the following? (5)

A
  • psychoeducation
  • motivational interviewing
  • behavior modification
  • cognitive behavioral therapy
  • support groups
46
Q

Trauma Rehabilitation
* Major cause of what?
* What is leading cause of death for Americans aged 1 to 44 years?
* Top mechanisms oftraumatic injuries include what?

A
  • Major cause of disability and death for individuals in the United States.
  • Unintentional injuries, homicide, and suicide is leading cause of death for Americans aged 1 to 44 years.
  • Top mechanisms oftraumatic injuries include falls, motor vehicle accidents and other transportation accidents.
47
Q

Trauma Rehabilitation
* Role can include what?
* Initial team focus is often what?

A
  • Role can include an initial evaluation, documentation of the patient’sinjury, and deciding what, if any, therapy can be initiated based on patient’s status.
  • Initial team focus is often a preventive nature, centered on preventing morbidity associated with immobility, positioning and nutrition.
48
Q

Evaluation of the Patient Requiring Trauma Rehabilitation
* Focuses on what?
* Ongoing evaluation after what?

A
  • Focuses on rapidly assessing key systems and organs necessary for sustaining life and maintaining function.
  • Ongoing evaluation after stabilization seeks to clarify the extent of an individual’s injuries as well as current and future functional status
49
Q

Evaluation of the Patient Requiring Trauma Rehabilitation
* What are the key systems and organs that need to be evaluated?

A
  • Head and spinal clearance
  • pulmonary function
  • gastrointestinal function and nutrition status
  • skin integrity
  • functional changes associated with prolonged hospitalization->deconditioning
50
Q

Common Traumatic Injuries Requiring Rehabilitation: Spinal cord injury
* Primary issue is what?
* Next involves what?

A
  • Primary issue is spinal and medical stabilization
  • Next involves evaluation of potential associated injuries
51
Q

Common Traumatic Injuries Requiring Rehabilitation
* What are the Complications and trauma care issues of spinal cord injury ? (3)

A
  • Respiratory function
  • Cardiovascular function
  • Gastrointestinal function – paralytic ileus
52
Q

Common Traumatic Injuries Requiring Rehabilitation: prognosis of spinal cord injury
* Future what?
* Balance issues relating to what?

A

Future functioning status

Balance issues relating to patient/family hopes and fears stemming from injury with need to convey truthful information
* What were the patient’s expectations if in this condition

53
Q

Traumatic brain injury:
* What is the gold standard for measurement of TBI severity? What score is coma?

A

MOI, associated injuries, and the GCS which is the gold standard for measurement of TBI severity.
* Score less than 8 is defined as a coma

54
Q

What are the Complications and trauma care issues of traumatic brian injury?

A
  • Changes in GCS require evaluation for infection, DVT and pulmonary embolism.
  • Agitation can be secondary to pain, confusion, fatigue, frustration or combination of these. Managementfocuses onenvironmental changes,if needed, then adding medications.
55
Q

What is the prognosis of traumatic brain injury?

A
  • Length of coma has been shown to correlate to prognosis, severe disability is unlikely when length of coma is less than two weeks.
  • Also included is length of post traumatic amnesia,patient age and GCS.
56
Q

Common Traumatic Injuries RequiringRehabilitation
* What can happen with fractures?

A

Multiple trauma may have bony fractures of one or more bones of their extremities.

57
Q

Common Traumatic Injuries RequiringRehabilitation:
* What are all the complications and trauma care issues with fractures?

A
  • Risk of developing acute compartment syndrome-> 6 Ps (pain,pallor, paresthesia, pulselessness, poikilothermic, which are changes in temperature and paralysis)
  • Fractures of the tibia are the most common for compartment syndrome followed by fracture of ulna and radius.
  • Evaluate for peripheral nerve injuries of either a complete or incomplete nature->Example mid shaft humeral fractures,12-19% are associated with a radial nerve injury.
58
Q

Common Traumatic Injuries RequiringRehabilitation
* What will you need with amputation?

A

Will need additional rehabilitation services to include pain management and additional symptoms with patients who undergo acute amputation from traumatic injury.

59
Q

Common Traumatic Injuries RequiringRehabilitation
* What are the complications and trauma care issues with amputation?(4)

A
  • Phantom limb pain
  • Edema
  • Contractures – ROM exercises early
  • Prosthetics->Must know what to expect from a functional standpoint
60
Q

Common Traumatic Injuries RequiringRehabilitation
* What do gunshot injuries cause? Bullet does not need to do what?

A
  • Cause massive tissue damage relative to small size of the missiles.
  • Bullet does not necessarily travel in a straight line and can spin end over end during penetration.
61
Q

Common Traumatic Injuries RequiringRehabilitation
* What are the complications and trauma care issues of GUNS? (4)

A
  • Treatment generally surgical with standard wound care and monitoring for signs of infection.
  • Tetanus prophylaxis should be updated.
  • Wounds can result in MSK, spinal cord injury, visceral injuries or TBI.
  • Self-inflicted wounds should involve a psychologist.
62
Q

Post Acute Care of the Trauma Rehabilitation Patient
* Provide input for what?

A

Provide input for preparation for patient discharge from acute care hospital to post-acute care setting.

63
Q

Post Acute Care of the Trauma Rehabilitation Patient
* What are the post acute trauma considerations? (7)

A
  • Medical
  • Functional
  • Social
  • Financial – can they afford the center
  • Geographic – how does location factor into family dynamics
  • Eligibility – covered by insurance
  • Choice – what if they do not have a choice in the center they have to go to
64
Q

Medical Rehabilitation
* What is primary care

A

Primary care is a coordinated, comprehensive, and personal care available on both a first-contact and a continuous basis.

65
Q

Medical Rehabilitation
* Primary care can be defined by serveral tasks? (6)

A
  • Medical diagnosis and treatment
  • Psychological diagnosis and treatment
  • Personal support of patients of all backgrounds
  • Communication of information about diagnosis, treatment, prevention, and prognosis.
  • Maintenance of patients with chronic illness
  • Prevention of disability and disease through detection, education, behavioral change, and preventive treatment.
66
Q

Pharmacotherapy
* Pharmacologic agents continue to play an important role in what?

A

Pharmacologic agents continue to play an important role in management of the patient’s rehabilitation course

67
Q

Pharmacotherapy: Spasticity
* Motor neuron disorders leads to what?

A

Motor neuron disorder leads to an abnormal increase in muscle tone secondary to hyperexcitability of the stretch reflex.

68
Q

Pharmacotherapy: Spasticity
* What are the four oral antispasiticity agents? What do they do?

A

Four approved by the FDA for spasticity management which have a systemic effect, reducing generalized muscle tone (caution is advised in patients with liver disease)
* Baclofen
* Diazepam
* Tizanidine
* Dantrolene

TBD(D)

69
Q

Pharmacotherapy: Spasticity
* What is the injectable antispasiticity agent?

A

Botulinum toxin – denervation and improvement of spasticity, takes effect in 24-72 hours, peak in 4-6 weeks and can last 2-6 months.

70
Q

Pharmacotherapy: Traumatic brain injury
* Individuals who survive the brain injury sustain what?
* Medications help to improve what?

A
  • Individuals who survive the brain injury sustain physical, cognitive, and neurobehavioral deficits.
  • Medications help to improve cognition, attention, and arousal to include
71
Q

Pharmacotherapy: traumatic brain injury
* What are 5 common drugs used and what do they do?

A
  • Amphetamine (used in post-surgical conditions after tumor resection, TBI as well)
  • Amantadine – Osmolex – used as an antiviral and for Parkinson’s disease
  • Bromocriptine – treats hormone imbalance, tumor related symptoms and Parkinson’s disease
  • Carbidopa-levodopa
  • Modafinil – reduces extreme sleepiness due to narcolepsy and other sleep disorders

AM CAB

72
Q

Pharmacotherapy: Pain
* What is pain?
* Classified as what?
* Acute associated with what?

A
  • Unpleasant, subjective experience that is often a significant issue for patients who require physical and rehabilitative care.
  • Classified as either acute or chronic.
  • Acute associated with tissue damage, increased autonomic nervous activity and resolution with healing of injury.
73
Q

Pharmacotherapy: Pain
* Chronic pain extends beyond what?
* Further separated into what?

A
  • Chronic pain extends beyond the expected period of healing, has no protective function, degrades health and function, and contributes to depressed mood.
  • Further separated into nociceptive pain refers to pain that arises from actual or potential tissue damage to sensory neurons that respond to harmful stimuli. Protective measure.
74
Q

Pharmacotherapy: VTE
* What is the goal?
* What is the Mainstay of VTE prevention ?

A
  • Goal is to prevent the occurrence of venous thromboembolism.
  • Mainstay of VTE prevention is prophylaxis using pneumatic compression devices and pharmacologic agents.
75
Q

What are the Four medications commonly prescribed for VTE prevention?

A
  • Unfractionated heparin
  • Low molecular weight heparin
  • Warfarin
  • Xarelto
76
Q

Unfractionated Heparin
* Dual function as what?
* Administered how?
* For immediate reversal of heparin, give what?
* If on a drip, usually loses its function when?

A
  • Dual function as an anticoagulant and an antithrombotic.
  • Administered subcutaneously.
  • For immediate reversal of heparin, administration of protamine sulfate.
  • If on a drip, usually loses its function after a few hours.
77
Q

Low-Molecular-Weight Heparin
* What is it?
* Results in what?
* What are the SE?
* Reversal involves administration of what?

A
  • Derived from standard heparin, Lovenox.
  • Results in higher bioavailability, longer half-life, and less nonspecific binding of plasma proteins.
  • Side effects generally same as heparin and include bleeding, bruising.
  • Reversal involves administration of NovoSeven (recombinant activated factor VII) , protamine is only partially effective in reversal.
78
Q

Warfarin
* What is the MOA?
* Absorbed how?
* How long does it take for stable loading odse?
* What is the half life?

A
  • Mechanism of action involves inhibition of liver synthesis of vitamin K-dependent coagulation factors.
  • Absorbed rapidly in the GI tract.
  • 36-72 hours requiredto attain a stable loading dose.
  • Long half-life, 20-60 hours.
79
Q

Warfarin
* INR is used to what?
* What are the SE?
* Reversalinvolves administration of what?

A
  • INR is used to monitor drug levels in the blood and effectiveness of therapy.
  • Side effectsinclude bleeding, bruising.
  • Reversalinvolves administration of vitamin K and prothrombin complex concentrate or fresh frozen plasma.
80
Q

Rivaroxaban
* Commonly referred to as what?
* Studies indicate what?
* No effective what?

A
  • Commonly referred to as Xarelto.
  • Studies indicate as effective and safe as subcutaneous LMWH in preventing VTE in patients with total hip or knee arthroplasty.
  • No effective reversal treatment for complications of Xarelto.