Lecture 5 Mitosis & Cell cycle

Question 0

Organismal growth that occurs through mitotic activity is called?

Answer 0

Hyperplasia

Question 1

In the S phase, What does the MCM detachment from the operator prevent?

Answer 1

duplicating the same DNA twice.

Question 2

meiosis is only used by which cells?

Answer 2

Germ

Question 3

T/F?

The resulting daughter cells are genetically identical to each other and are haploid.

Answer 3

F, they are haploid BUT NOT identical ( crossing over)

Question 4

Name the 4 cell cycles?

Answer 4

• Centrosomal cycle
• Nuclear cycle
• Cytoplasmic cycle
• Chromosomal cycle

Question 5

What happens in the centrosomal cycle?

Answer 5

The Centrioles duplicate and separate

Question 6

what happens in Nuclear cycle?

Answer 6

Lamins disassemble and reassemble

Question 7

What occurs in cytoplasmic cycle?

Answer 7

Cytoplasm increases in volume and there is slow division

Question 8

What occurs in The Chromosomal Cycle?

Answer 8

DNA unwinds and Winds

Question 9

Centrioles are nucleation sites for what?

Answer 9

Mitochondria

Question 10

When do centrioles duplicate? and then separate?

Answer 10

interphase

Prophase

Question 11

what happens in the Nuclear cycle when lamins are phosphoylated and dephosphorylated?

Answer 11

become unstable and They disassemble

they reassemble

Question 12

•The opening of the double helix and unwinding of the DNA molecule is carried out by enzymes referred to as ____________, a form of ____________.

Answer 12

helicases

topoisomerases

Question 13

Progression through the cell cycle is controlled by

__________ __________that have been conserved from yeasts to mammals.

Answer 13

protein kinases

Question 14

Throughout the cell cycle the concentration changes for ________ but not for __________?
choices, cyclins, CDKs

Answer 14

cyclins

cdk

Question 15

In G1 the Amount of chromosomal material is referred to as #___n?
After S phase #___n?

Answer 15

2n

4n

Question 16

In G1 the concentration of Cyclin ___ increases and binds with Cdk___ to form _____?

Answer 16

E
2
MPF

Question 17

•Activated Cyclin__ & Cdk__ kinase leads to activities necessary for mitosis.

Answer 17

A

1

Question 18

Which cyclin and Cdk are responsible for binding in Mitosis to help with its completion?

Answer 18

B (blast off)

1 (last step for blast off)

Question 19

Where does the Start site of the cell cycle occur and what does it mean?

Answer 19

end of G1 and once it goes through this site, it has committed to go through S phase and the rest of the cell cycle.

Question 20

at the end of S phase ____cyclins are degraded &

___cyclin concentration begins to increase.

Answer 20

E

A

Question 21

For MPF
_________________inhibits the complex and allows it to accumulate throughout G2. ______________is necessary to activate the kinase allowing for the entry of the cell into the M phase.

Answer 21

Phosphorylation

Dephosphorylation