Lecture 5 Mitosis & Cell cycle Flashcards
Organismal growth that occurs through mitotic activity is called?
Hyperplasia
In the S phase, What does the MCM detachment from the operator prevent?
duplicating the same DNA twice.
meiosis is only used by which cells?
Germ
T/F?
The resulting daughter cells are genetically identical to each other and are haploid.
F, they are haploid BUT NOT identical ( crossing over)
Name the 4 cell cycles?
- Centrosomal cycle
- Nuclear cycle
- Cytoplasmic cycle
- Chromosomal cycle
What happens in the centrosomal cycle?
The Centrioles duplicate and separate
what happens in Nuclear cycle?
Lamins disassemble and reassemble
What occurs in cytoplasmic cycle?
Cytoplasm increases in volume and there is slow division
What occurs in The Chromosomal Cycle?
DNA unwinds and Winds
Centrioles are nucleation sites for what?
Mitochondria
When do centrioles duplicate? and then separate?
interphase
Prophase
what happens in the Nuclear cycle when lamins are phosphoylated and dephosphorylated?
become unstable and They disassemble
they reassemble
•The opening of the double helix and unwinding of the DNA molecule is carried out by enzymes referred to as ____________, a form of ____________.
helicases
topoisomerases
Progression through the cell cycle is controlled by
__________ __________that have been conserved from yeasts to mammals.
protein kinases
Throughout the cell cycle the concentration changes for ________ but not for __________?
choices, cyclins, CDKs
cyclins
cdk
In G1 the Amount of chromosomal material is referred to as #___n?
After S phase #___n?
2n
4n
In G1 the concentration of Cyclin ___ increases and binds with Cdk___ to form _____?
E
2
MPF
•Activated Cyclin__ & Cdk__ kinase leads to activities necessary for mitosis.
A
1
Which cyclin and Cdk are responsible for binding in Mitosis to help with its completion?
B (blast off)
1 (last step for blast off)
Where does the Start site of the cell cycle occur and what does it mean?
end of G1 and once it goes through this site, it has committed to go through S phase and the rest of the cell cycle.
at the end of S phase ____cyclins are degraded &
___cyclin concentration begins to increase.
E
A
For MPF
_________________inhibits the complex and allows it to accumulate throughout G2. ______________is necessary to activate the kinase allowing for the entry of the cell into the M phase.
Phosphorylation
Dephosphorylation
