Lecture 5: Disease in non-Western countries Flashcards

1
Q

Double burden of disease

A

more non-communicable/chronic disease in high income countries, but still a lot of communicable diseases in low-income countries

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2
Q

Double burden of malnutrition

A

coexistence of undernutrition together with diet-related non-communicable diseases like overweight and obesity

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3
Q

SDI

A

socio-demographic index

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4
Q

Selection bias

A

bias resulting from selection of people into or out of the study

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5
Q

Ascertainment of detection bias

A

if an individual’s chance of being diagnosed is related to whether they have been exposed to the factor of interest

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6
Q

The healthy-worker effect

A

people who are working have to be healthy enough to do their jobs

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7
Q

Information bias

A

biased exposure or outcome relation resulting from errors in exposure and/or outcome

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8
Q

Confounding

A

effect of an extraneous factor is mistaken for/mixed with the actual exposure effect
3 criteria:
- Confounder is a risk factor
- Confounder is associated with exposure of interest
- Confounder is not an intermediate between exposure and outcome

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9
Q

Randomisation

A

allocate people to study groups at random

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10
Q

Restriction

A

restricting a study to a particular age or socioeconomic group

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11
Q

Matching

A

match subjects on the presence or absence of the confounding variable

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12
Q

Effect measure modification

A

association differs across levels of a third factor

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13
Q

Individual matching

A

same distribution in case and control group

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14
Q

Frequency matching

A

for each ‘smoking’ case, use a ‘smoking’ control

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15
Q

Prevalence ratio

A

prevalence in exposed / prevalence in unexposed

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16
Q

IRR

A

incidence rate ratio; incidence rate in exposed / incidence rate in unexposed

17
Q

IPR

A

incidence proportion ratio; incidence proportion in exposed / incidence proportion in unexposed

18
Q

Odds ratio

A

relative risk

19
Q

Attributable risk

A

measures the actual amount of disease that can be attributed to a particular exposure; incidence rate exposed - incidence rate unexposed. Or: incidence proportion exposed - incidence proportion unexposed

20
Q

AF

A

attributable fraction; attributable risk / incidence in exposed * 100%

21
Q

PAR

A

population attributable risk; incidence rate population - incidence rate unexposed. Or: incidence proportion population - incidence proportion unexposed. Or: attributable risk * prevalence

22
Q

PAF

A

population attributable fraction; PAR / incidence in total population * 100%

23
Q

NNT

A

number needed to treat; 1 / AR

24
Q

ARR

A

absolute risk reduction; same as attributable risk

25
Q

Placebo effect

A

the measurable, observable, or felt improvement in health or behaviour not attributable to a medication or treatment that has been given