Lecture 5 - Blood vessels Flashcards
Four layers of blood vessels:
Centre of vessels
First layer after the lumen
Second layer after the lumen
Third layer after the lumen
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Lumen
Tunica intima
Tunica media
Tunica adventitia
Tunica intima: what is it and what is it made of?
Thinnest, lined with simple squamous, sub endothelial connective tissue, basal lamina of the epithelial cells
Tunica media: what is it made of?
Smooth muscle fibres in loose connective tissue
Tunica adventitia: what does it merge with and what may it contain
Merges with surrounding connective tissue, may contain vasa vasorum (vessels to the vessel)
Types of arteries
Elastic, muscular, arterioles
Elastic arteries: what does it do, what diameter, adaptions, and what is an example?
Withstand pressure changes during the cardiac cycle and esnure continuous blood flow
Can be up to 2.5cm
Thick tunica media with many elastic fibres and few smooth muscle cells
The aorta -> brachiocephalic -> common carotid
Muscular arteries: what do they do, diameter, adaptions, examples?
Vasodilates or vasoconstricts to meet the needs of the organ
0.5mm to 4mm
Lots of smooth muscle cells in tunica media, internal elastic laminae (IEL between intima and media) and external elastic laminae (EEL between media and externa), thick tunica externa
Femoral, brachial
Arterioles: what does it do, diameter, adaptions?
Capable of vasoconstriction & vasodilation so involved in blood pressure control
<30 micrometers
Poorly defined adventia, only one or two layers of smooth muscle in media
Capillaries: what do they do, what adaptions for their function, blood flow speed, diameter, three types of capillaries?
Found near almost every cell, connects arterioles and venules, site of 2-way gaseous and material exchange
Thin walls which allow for easier material exchange
Blood flows very slowly
Roughly 8 micrometres in diameter
Continuous, fenestrated, and sinusoidal
Continuous capillaries: where are they found?
Majority are continuous and these are found in the lungs and skleletal and smooth muscle
Fenestrated capillaries: function in the body, adaptions and what do they do?
Absorption in the kidney, choroid plexus, and the endocrine glands
Pores (fenestrations) allowing the exchange of water or large solutes (small polypeptides)
Sinusoidal capillaries: function in the body, adaptions and what do they do?
Exchange of large solutes (plasma proteins)
Incomplete or absent BM, specialised lining cells (phagocytes in the liver engulfing damaged WBCs)
Metarterioles
One supplies blood to a whole capillary bed
Constriction of a metarteriole will reduce blood flow to the bed it’s connected to
Precapillary sphincter
Guards the entrance to each capillary, dilation or constriction will either increase or decrease blood flow
Arteriovenous anastomes
Form direct connection between the arteriole and venule
Plays an important role in temperature regulation