Lecture 5 Flashcards
What is the mechanism of fast adaptation?
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How is the concentration gradient of Ca created to be able to form a difference in concentration outside and inside?
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How much work is done by one Ca ion binding to one channel? Units?
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What is the mechanism of slow adaptation? What is the role of the myosin molecules? What are the other components involved?
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What is the classical gating swing model? What happens?
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What is the equation involved in the gating swing model? What is it for?
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What is the order of magnitude values?
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What is the current model of the channels and gating swing?
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What is the motion during opening of a mechanosensitive ion channel? What questions does this raise?
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What is the configuration of the hair bundle on a microscopic level?
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What is the hydrophobic mismatch? What does it result in?
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What does hydrophobic mismatch depend on? What are the features?
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What happens when one small and one large protein is embedded into the lipid bilayer?
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What are the elastic potentials between two MscL proteins in different conformations? What effect does distance have on it?
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What happens as a result of this interaction between closed - open channels and open-open channels?
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