Lecture 4 Flashcards
What is the mechano-transduction that occurs in hair cells? What are the components involved?
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What is the classical gating spring model?
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What is GATING?
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What is GATING SPRING?
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What is the probability formula of the channel gate opening? What are the components?
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What is the order of the magnitude values?
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How does the active process work?
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How is calcium involved?
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How to calculate how much work one Ca ion can do to close one channel? What is the formula?
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What is the whole cycle?
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What is the frequency determined by?
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Is the hair bundle a good resonator? Why? Thomas Gold’s point?
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How must the hair bundle minimize viscous friction?
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How does it not let the liquid move? What is the relation motion between the stereocilia in a hair bundle?
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What is the extent of liquid movement between stereocilia dependent on?
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What is the problem with measuring the motion in the hair bundles?
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How has this problem been overcome? How to measure the relative motions between stereocilia?
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What is the interferometer? How does it work?
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What did the interferometer show as results of the movement of the stereocilia?
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What is the relative mode? What does it help understand?
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How can the non-linearity property of the hair bundle stiffness be used to measure the size of the gaps between the stereocilia?
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What is the gap between the stereocilia? What does this show?
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How does the stereocilia/ hair bundle move in a finite element model with no tip links? What changes in increased frequency?
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What is the change in viscous drag with frequency? Why?
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