Lecture 4 Flashcards

1
Q

What is the mechano-transduction that occurs in hair cells? What are the components involved?

A

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2
Q

What is the classical gating spring model?

A

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3
Q

What is GATING?

A

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4
Q

What is GATING SPRING?

A

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5
Q

What is the probability formula of the channel gate opening? What are the components?

A

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6
Q

What is the order of the magnitude values?

A

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7
Q

How does the active process work?

A

sadasd

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8
Q

How is calcium involved?

A

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9
Q

How to calculate how much work one Ca ion can do to close one channel? What is the formula?

A

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10
Q

What is the whole cycle?

A

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11
Q

What is the frequency determined by?

A

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12
Q

Is the hair bundle a good resonator? Why? Thomas Gold’s point?

A

dwasdf

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13
Q

How must the hair bundle minimize viscous friction?

A

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14
Q

How does it not let the liquid move? What is the relation motion between the stereocilia in a hair bundle?

A

adsfsdf

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15
Q

What is the extent of liquid movement between stereocilia dependent on?

A

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16
Q

What is the problem with measuring the motion in the hair bundles?

A

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17
Q

How has this problem been overcome? How to measure the relative motions between stereocilia?

A

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18
Q

What is the interferometer? How does it work?

A

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19
Q

What did the interferometer show as results of the movement of the stereocilia?

A

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20
Q

What is the relative mode? What does it help understand?

A

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21
Q

How can the non-linearity property of the hair bundle stiffness be used to measure the size of the gaps between the stereocilia?

A

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22
Q

What is the gap between the stereocilia? What does this show?

A

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23
Q

How does the stereocilia/ hair bundle move in a finite element model with no tip links? What changes in increased frequency?

A

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24
Q

What is the change in viscous drag with frequency? Why?

A

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25
Q

How does the stereocilia/ hair bundle move in a model with tip links added? What changes in increased frequency?

A

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26
Q

What is fluid coupling?

A

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27
Q

What is elastic coupling?

A

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28
Q

What happens in the model with horizontal top connectors on all stereocilia?

A

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29
Q

What happens to the drag in this model? What does this show?

A

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30
Q

Why are stereocilia tightly clustered in a hair bundle? What shows this?

A

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