Lecture 5 Flashcards

Vestibular System

1
Q

The vestibular system is a sensory
system located in:

A

the inner ear

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2
Q

The vestibular system processes sensory information underlying (3):

A

➢ Motion
➢ Head position
➢ Spatial orientation relative to gravity

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3
Q

The vestibular system is responsible for

A

the body’s equilibrium

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4
Q

The vestibular system is responsible for
the body’s equilibrium; It helps to
stabilize

A

gaze, head, and postur

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5
Q

vestibular system uses specialized sensory neurons __ to transduce physical motion into
neural impulses.

A

hair cells

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6
Q

The vestibular labyrinth composed of two organs:

A

(1) Otolith organs (Utricle & Saccule)
(2) Semicircular canals (Superior, Posterior & Horizontal)

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7
Q

Otolith organs:

A

Utricle & Saccule

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8
Q

Semicircular canals:

A

Superior, Posterior & Horizontal

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9
Q

Vestibular hair cells:

A

Flask-shaped epithelial cells with a
bundle of hair-like processes
(STEROCILLIA) attached between each
other by a TIP LINK.

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10
Q

Vestibular hair cells: kinocillum:

A

the longest process

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11
Q

Hair cell is very sensible to

A

movement

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12
Q

Hair cell is very sensible to movement.
The movement changes

A

its membrane
potential

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13
Q

When the hairs (sterocillia) move toward
Kinocillum =

A

depolarization (excitation)

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14
Q

When the hairs (sterocillia) move far from the
Kinocillum =

A

hyperpolarization (inhibition)

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15
Q

When the sterocillia (hair bundle) is deflected toward
the kinocilium,

A

tip links are stretched and directly
open K+
-selective channels near the tips of the
stereocilia, allowing K+ to flow into the hair cell and
depolarize the hair cell.

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16
Q

The resulting depolarization of the hair cell

A

opens Ca2+
channels in the cell body, allowing Ca2+ entry and
release of neurotransmitter to excite the post–synaptic
neuron (vestibular nerve) and the electrical signal is
sent to the brain.

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17
Q

the hair cell (receptor) is ___ to
the nerve.

A

not directly attached

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18
Q

2 otolith organs:

A

(1) utricle and
(2) saccule

19
Q

Each otolith organ contains (3) :

A

(1) Macula
(2) Gelatinous layer
(3) Otolithic membrane

20
Q

Macula:

A

sensory epithelia containing
the soma (cell body) of hair cells and
supporting cells,

21
Q

Gelatinous layer:

A

containing hair
bundles

22
Q

Otolithic membrane

A

Fibrous layer
embedding ‘Otoconia’: crystals of
calcium carbonate (ear rocks, stones).

23
Q

Otoconia

A

crystals of
calcium carbonate (ear rocks, stones)

24
Q

Otolith organs detect __ movements

A

linear

25
Q

Otolith organs detect linear movements:

A

(1) Translational movements of the head (i.e., forward & backward movements)

(2) Static head movement relative to the gravitational axis (i.e., head tilts)

26
Q

The otoconia (ear rocks) make

A

the otolithic membrane heavier than the
structures and fluids surrounding it.

27
Q

When the head tilts or moves, gravity causes the otolithic membrane to

A

shift relative to the macula. The hairs in the gelatinous layer are
displaced and a receptor potential is generated.

28
Q

The utricle is positioned

A

horizontally

29
Q

The utricle detects:

A

the horizontal translational movements of the head
(i.e., moving forward or backward = moving in X axe):
➢ e.g., walking, being in a moving car.

30
Q

The saccule is positioned

A

vertically

31
Q

The saccule detects

A

the vertical translational movements of the head
(i.e., moving up & down = moving in Y axe):
➢ e.g., being in a moving elevator.

32
Q

Semicircular canals

A

Fluid-filled tubes specialized for
responding to rotations of the
head.

33
Q

3 semicircular canals:

A

(1) Horizontal
(2) Superior
(3) Posterior

34
Q

Horizontal semicircular canal:

A

turning left & right (No sign)

35
Q

superior semicircular canal:

A

nodding up & down (Yes sign)

36
Q

posterior semicircular canal:

A

tilting to a side (towards the shoulders)

37
Q

Semicircular canals: AMPULLA:

A

an enlargement at the base of each
semicircular canal. It houses the hair cells.

38
Q

Semicircular canals: the hair bundles extend out into a gelatinous mass,

A

the cupula

39
Q

semicircular canals: endolymph fluid:

A

circulates in the
semicircular canal.

40
Q

semicircular canals: the rotation of the head causes the movement of the:

A

endolymph fluid in the
opposite direction of the head movement,
which pushes the cupula and displaces the
hair bundles. As a result, the hair cell is
depolarized and receptor potential is
generated, the electrical signal sent to the
brain.

41
Q

Each semicircular canal works in

A

opposite manner with its pair
located on the other side of the
head

42
Q

A tilt of the head to one side
(e.g. right) activates the hair
cells in the

A

right horizontal
canal but inhibits the hair cells
in the left horizontal canal

43
Q

slide 14 15

A
44
Q

The Vestibulo-Ocular
Reflex (VOR) produces

A

eye
movements that counter
head movements (i.e.,
moving the eyes in opposing
direction to the head), thus
permitting the gaze to
remain fixed on a particular
point: