lecture 43 pt 2 Flashcards
campbell - tx of non-motor symptoms PD
what are the non-PCOL options for treating constipation associated with PD?
evaluate for medications causing constipation
increase fluid intake and physical activity (if able)
what are the pharm options for constipation associated with PD?
stool softeners/laxatives or probiotics may be effective
what are the treatment options for insomnia associated with PD?
non-pharm counseling
melatonin
what medications should be avoided due to causing insomnia?
benzodiazepines (diazepam, lorazepam, etc)
what are the treatment options for orthostatic hypotension associated with PD?
non-pharm counseling
admin midodrine or droxidopa
use medical equipment to stabilize patients
what are the treatment options for anxiety/depression associated with PD?
cognitive behavioral therapy (or non-pharm approach)
use an SSRI/SNRI
what medications should be avoided or cautioned when pt has anxiety, depression associated with PD?
avoid - benzodiazepines
caution - tricyclic antidepressants (TCAs)
what are the treatment options for dementia associated with PD?
cholinesterase inhibitors like donepezil or rivastigmine
what drugs should be avoided in dementia associated with PD?
anticholinergics
benzodiazepines
antihistamines
sedatives
what are the treatment options for psychosis/delirium associated with PD?
reduce PD medication dose if appropriate
use pimavenserin or atypical antipsychotics (clozapine, quetiapine)
what is pimavanserin?
newish antipsychotic used for PD induced psychosis
what drugs should be avoided in psychosis/delirium associated with PD?
haloperidol
olanzapine
paliperidone
risperidone
what are the non-motor symptoms of PD?
anxiety/depression
constipation
dementia
insomnia
orthostatic hypotension
psychosis/delirium
sexual dysfunction
