Lecture 4: Water, concentrations, acids and bases Flashcards
Mole?
Quantity used to measure an amount of substance.
Calculating number of moles?
n (moles) = mass (grams) / molecular weight (Da)
Avogadros number?
6.022 x 10^23
Calculating concentration?
C (concentration) = n (number of moles of substance) / volume (litres)
pH values?
14 is basic, 7 is neutral, 0 is acidic
Disassociation of water?
Water can disassociate resulting in hydronium ions and hydroxide ions. Changes in concentration of these ions can have a great effect on living organisms.
What is equation for disassociation of water?
2H20 = hydronium ion (H30+) + hydroxide ion (OH-)
Coordinate covalent bonds?
The hydronium ion is actually a coordinate covalent bond, where both electrons in the bond with the additional H+ come from water itself. The third proton can be exchanged with other ions with a net negative charge (e.g. OH- group to make H20) or molecules with a lone pair (e.g. NH3 to make NH4+)
How to measure acidity of a solution?
Measured by the concentration of H30+ ions present.
Acid?
Acids are substances which tend to donate a proton (H+).
Base?
Bases are substances which tend to accept a proton (H+).
Acid and Base equation.
HA (acid) + OH- (base) = A- (salt) + H20 (water)
Normal average pH value for body fluids?
7.4
What is pH threshold?
if body pH gets below 6.8 or above 8.0, you could die.
What is a buffer?
The buffer system absorbs protons by removing them from hydronium ions through a reaction with a salt ion. The buffer can also donate protons by generating hydronium ions when the pH gets too high.