lecture 4 visceral pain Flashcards
what does the enteric nervous system consist of
400-600 million intrinsic neurones that extend most of length of GIT
what is the ENS arranged in
glanglionated plexuses with interconnecting bundles of unmyelinated nerve fibres
what is the function of the ENS
enable GIT to preform basic reflex functions of secretion, absorption, mixing and gut movement without influence of CNS or ANS
how does the CNS communicate with ENS intrinsic neurones to modulate GIT functions
via sympathetic and parasympathetic nerves
where do axons of intrinsic neurones of ENS also project to
sympathetic ganglia, pancreas, gall bladder, trachea, spinal cord, brain stem
structure of GIT (lumen to exterior)
lumen - mucosa (lamina propria and muscularis mucosae; glands) - MALT - submucosa (glands; submucosal plexus of Meissner) - muscularis (for peristalsis; circular then myenteric plexus of Auerbach, then longitudinal) - serosa (epithelium) - mesentery (nerve and artery)
where is intrinsic network of neurones of ENS situated
2 plexuses in tissues of gut wall from oesophagus to anus (submucosal and muscularis)
structure and divisions of ANS
different to somatic NS (ganglia, myelination, neurotransmitters); 2 divisions (sympathetic and parasympathetic) which innervate organs of abdomen and pelvis
where does ANS arise from
different anatomical regions of CNS; sympathetic from spinal cord segments T1-L2, parasympathetic from cranial nerves III, VII, IX, X in brain stem, and spinal cord segments S2-S4
slide 8
sympathetic chain; ganglia form separate spinal cord segments; parasympathetic: vagus to abdomen, sacral parasympathetic outflow to pelvis
functions of efferent ANS nerves to abdomen
motor to smooth muscle; secretomotor to glands
functions of afferent ANS nerves to abdomen
sympathetic: pain; parasympathetic: specific functional sensation e.g. stretch
sympathetic nerves to abdomen (visceral)
from T1-L2; sympathetic trunks, diaphragm, splanchnic (visceral) nerves, coeliac ganglion
vagus nerves to abdomen (visceral)
left and right vagus nerves splitting into anterior and posterior vagul trunks
sympathetic chain to abdomen: greater splanchnic nerve level
T5-T9
sympathetic chain to abdomen: lesser splanchnic nerve level
T10-T11
sympathetic chain to abdomen: least splanchnic nerve level
T12
nerves from lumbar sympathetic chain
go to different parts; all splanchnic nerves and autonomic plexus won’t be retained in dissection
parasympathetic supply
vagus (cranial nerve X) and S2-S4
what ANS division goes to peripheral vessels and skin
sympathetic