Lecture 4 - Regulation of fibrin clot structure Flashcards

1
Q

When is tissue factor released?

A

Damage to the blood vessel wall

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2
Q

Describe one way in which fibrin is activated

A

TF activates factor VIIa
Factor VIIa activates factors Xa
Factor Xa activates thrombin
thrombin converts fibrinogen to fibrin

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3
Q

What are the regions of fibrinogen molecule

A

2 D regions

1 E region

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4
Q

what connects the D region to teh E region

A

coiled coil region

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5
Q

What is present in the D region

A

1 gamma peptide

1 beta peptide

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