Lecture 4 - Regulation of fibrin clot structure Flashcards
1
Q
When is tissue factor released?
A
Damage to the blood vessel wall
2
Q
Describe one way in which fibrin is activated
A
TF activates factor VIIa
Factor VIIa activates factors Xa
Factor Xa activates thrombin
thrombin converts fibrinogen to fibrin
3
Q
What are the regions of fibrinogen molecule
A
2 D regions
1 E region
4
Q
what connects the D region to teh E region
A
coiled coil region
5
Q
What is present in the D region
A
1 gamma peptide
1 beta peptide
