Lecture 1 - Extra reading

Question 1

What does the position and slope of the LV ESPVR represent

Answer 1

Hidekatsu Fukuta, 2008
flattening and shifting to the right occurs when there is depressed myocardial contraction function.
More vertical indicates increased contractility

Question 2

What can the position of the LV ESPVR slope be used for?

Answer 2

Hidekatsu Fukuta, 2008

measurement of contractile state

Question 3

Which heart failure is more common?

Answer 3

systolic

brian d hoit , 2007

Question 4

What occurs as a result of diastolic dysfunction

Answer 4

impaired LV relaxation decreases early ventricular filling and shifts the burden of maintaining adequate end-diastolic volume to the atria
brian d hoit , 2007

Question 5

What does diastole depend on?

Answer 5

Speed and synchrony of myocardial relaxation, inactivation, loading conditions, viscoelasticty, HR , atrial function
brian d hoit , 2007

Question 6

what happens in relaxation on a cellular level?

Answer 6

return of sacromere to original resting length through a series of steps which involve the removal of calcium from troponin C
brian d hoit , 2007