Lecture 4: Endocrine Flashcards
What is the endocrine system?
A system of hormone-secreting glands that regulate and coordinate many body functions
List the endocrine organs (7)
- Hypothalamus (brain)
- Pituitary gland (brain)
- Pineal gland (brain)
- Thymus → Thyroid + Parathyroid glands (larynx)
- Adrenal gland (kidneys)
- Pancreas (abdomen)
- Gonads (ovaries + testes)
Where is the binding site for steroid hormones?
Nucleus
Alters mRNA after binding
Where is the binding site for peptide hormones?
cell surface
GPCR → activates 2nd messengers
What are the functions of the hypothalamus (3)?
- Regulation of the pituitary gland:
- Axons travel down the pituitary stalk and synapse in the posterior pituitary
- Connections to the portal system (network of capillaries) allow the hypothalamus to stimulate the anterior pituitary to release hormones
Does the posterior pituitary gland produce its own hormones?
No
Pars Nervosa is the same as the ______ pituitary
posterior
What is the function of Herring bodies? Where are they located?
- store hormones from the hypothalamus
- located in the posterior pituitary
Does the anterior pituitary gland produce its own hormones?
Yes
What two hormones does the posterior pituitary secrete?
- Vassopressin (ADH)
- Oxytocin
Hypothalamus makes vassopressin + oxytocin → secreted by posterior pituitary
Pars Anterior is the same as the ______ pituitary
anterior
What two cells secrete hormones in the anterior pituitary?
- Acidophils
- Basophils
Only have acidophils in anterior pituitary
What two hormones do acidophils secrete?
- Growth Hormone (GH)
- Prolactin (PRL)
What hormones do basophils secrete (4)?
- Thyrotropin (TSH)
- Follitropin (FSH) or Leuteotropin (LH)
- Corticotropin (ACTH)
- Melanocyte stimulating hormone (MSH)
What are 1, 2, 3, and 4?
The cells circled in red secrete GH + PRL. What are these cells called?
Acidophils (pink stain)
The cells circled in dark blue secrete TSH, FSH, LH, ACTH, and MSH. What are these cells called?
Basophils (dark stain)
What type of cells are A, B, and C?
What two cells are shown in this image?
Axons and pituicytes
Identify C (red) and D (dark blue)
Identify A and B
What is the function of the pineal gland (pineal body)?
secretes melatonin = role in sleep
released by pinealocytes
How does daytime affect the pineal gland?
Daytime inhibits the pineal gland → no melatonin
How does nighttime affect the pineal gland?
Nighttime activates the pineal gland → secretes melatonin