Lecture 4: Control of HR Flashcards

1
Q

Sympathetic Neurons

A

short pre gang neuron axons
release ACh along post gang
long postgang axons relaease NE

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2
Q

Parasymp Neurons

A

long pregang neurons
axons relases Ach
short postgang axons release Ach

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3
Q

Cardiac cycle

A

events that happen in 1 heartbeat

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4
Q

systole

A

ejection

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5
Q

diastole

A

filling

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6
Q

cardiac cycle time

A

0.8 seconds at rest

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7
Q

heart rate monitored by

A

changes in ANS

ANS activity can be modified by circulating hormones, higher brain structure

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8
Q

Chronotropic Effects

A

effects of ANS on heart rate

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9
Q

Cardivascular Center

A

caudal protions of medulla oblongata

symp neurons that send nerve fibers to heart are here

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10
Q

HR control by Symp Brach of ANS

A

neourosn of CV center synapse on pregang neurons i
pregang synapse on postgang neurons
post gang send axons to SA and AV and cardiac muscle fibers

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11
Q

Control of HR by Symp Branch of ANS (whats released)

A

pregang release ACh onto post

post gang NE onto target cells

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12
Q

NE

A

postgang neurotransmitter for symp NS

Acivates beta1 receptors (widespread effects on cardiac nervous stuff

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13
Q

HR Control mechs

A

inc rate of depol in SA and AV nodes due to inc in Na contnent

Mech: neurons brought to threshold more frequently
inc in number of APs made per time

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14
Q

CV Center symp and parsymp centers

A

Fibers from cardiacceleatory: symp

“ “ cardioinhibitory center: parasymp

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15
Q

parasymp from CV center

A

send axons to heart via vagus nerves

VAGAL MOTORNEURONS

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16
Q

Vagal motorneurons

A

synapse directly on AV and SA nodes and atrial muscle fibers

relase ACh onto postgang cells: SLOW HR

17
Q

ACh incs

A

K permeability of cells

18
Q

Inc K perm result

A

Hyperpolarization of membrane
(K makes repol lower than regular RMP,)
takes longer to get to threshold

19
Q

Hormones that inc HR and contractility

A

epinephrine, thyroxine

20
Q

Hypocalcemia

A

reduced ionic calcium decr contractility

less ca in blood

21
Q

Hypercalcemia

A

dramitic inc of irritability leads to spastic contraction
too much calcium in blood
hyper response to small stim

22
Q

Hypernatremia

A

blocks heart contractility
b/c inhibited ca transport
too much Na, competes with Ca

23
Q

Hyperkalemia

A

blocks contraction= cardiac arrest

too much K, cant return to resting MP

24
Q

Calcium

A

= contractility