Lecture 4 - Cardiovascular system, Anatomy of the Heart (part I) Flashcards

1
Q

Level of organisation in the cardiovascular system

A

Cardiovascular system is made up of organs that consist of the heart (pump), arteries-carries what the heart is pumping (supply), veins-drains blood towards the heart/lymphatics-some fluid leaves the blood vascular system and gets into the surrounding interstitial tissues and that fluid we bring back into the cardiovascular system via lymphatics(drainage) and capillaries (exchange). These organs are made up of vascular tissue which is made up of connective tissue and cells. The cells consist of epithelia and muscle (cardiac muscle which is only found in the heart and smooth muscle which is on the walls of blood vessels)

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2
Q

Arteries

A

blood vessels that carry blood AWAY from the heart

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3
Q

Veins

A

blood vessels that carry blood TOWARDS the heart

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4
Q

Blood vascular system

A

A closed supply and drainage system, it is a continuous loop.

Pump at centre forming a loop taking blood out to a target tissue and returning it in a closed loop back to the heart

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5
Q

Lymphatic (vascular) system

A

An open-entry drainage system, it is a one way system

Some fluid can leave and get to the surrounding tissue. We have a mechanism of these porous finger like projections sitting in the tissue that can act like drainage channels that can bring the fluid back into the blood vascular space/bringing fluid back that has left the blood vascular space back into the blood vascular space

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6
Q

What two system make up the cardiovascular system?

A

Blood vascular system and the lymphatic (vascular) system

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7
Q

Systemic circulation

A

Systemic circulation carries oxygenated blood from the left ventricle, through the arteries, to the capillaries in the tissues of the body. From the tissue capillaries, the deoxygenated blood returns through a system of veins to the right atrium of the heart.

Circuit that sends oxygen-rich blood to the tissues of the body and brings oxygen-poor blood back to the heart

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8
Q

Veins and arteries - the lungs

A

On the right side we have an artery carrying deoxygenated blood under high pressure and velocity and this pushes that blood into the lungs for reoxygenation and from the lungs we have a vein carrying oxygenated blood back to the heart which is then pushed out into another big loop called the systemic circulation.

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9
Q

Systemic vs pulmonary circulation

A

The cardiovascular system is composed of two circulatory paths: pulmonary circulation, the circuit through the lungs where blood is oxygenated, and systemic circulation, the circuit through the rest of the body to provide oxygenated blood.

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10
Q

Pulmonary circulation

A

The deoxygenated blood shoots down from the right atrium to the right ventricle. The heart then pumps it out of the right ventricle and into the pulmonary arteries to begin pulmonary circulation. The blood moves to the lungs, exchanges carbon dioxide for oxygen, and returns to the left atrium.

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11
Q

Supply side of the cardiovascular system

A

Arteries are the only supply path
Major arteries are situated to avoid damage because they are carrying blood at high pressure and at high velocity and if damaged the ability to lose high volumes of blood is high e.g. deep in the trunk (free from injury on anterior surface); on flexor aspect of limbs (anterior surface of upper limbs (in anatomical) for example)
Important structures often receive simply from two sources (two separate arteries) - this protects these structures. For example in the hand there is the radial artery and the ulna artery, the brain has 4 because you don’t want any damage to be able to compromise the role of the brain
Arteries change their name at each major branch

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12
Q

Exchange network of the cardiovascular system

A

Capillaries of vaarying degrees of permeability …the permeability can change depending on the tissues demands. Permeability means how easy it is to cross from the blood to the surrounding tissues
Continuous (controlled, tight) - tight control over what can enter the capillaries, epithelial lining is a continuous cellular barrier
Fenestrated (leaky) - not big enough for blood cells to leave but make it easier for things in solution to enter or leave the capillary
Sinusoidal (very leaky) - for example in the liver

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13
Q

Drainage system of the cardiovascular system

A

3 pathways for drainage (away from exchange surfaces) …
Deep veins - run back win opposite direction to deep supply arteries
Superficial veins - veins on the back of the hands for example
Lymphatics

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14
Q

Why is it better to get a cut to a superficial vein?

A

Draining blood at lower pressure and lower velocity so if cut then you only need to apply light pressure to stop it

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15
Q

CSA of veins and arteries

A

Cross-sectional area of veins is at least twice that of arteries (to shift the same volume of blood per second). Otherwise there would be a volume mismatch and swelling would occur. To compensate for the difference in physiology between supply and drainage channels we need to make sure that veins have a greater CSA to make sure that we shift the same volume back to the heart per second as we are pumping to the target tissue per second.

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16
Q

Heart shape

A
Blunt, cone shaped 
Pointed end is called the apex 
Broad end (top) is called the base - major pipes come off of this part
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17
Q

Approximate size of heart

A

Size of the heart is approximately that of a closed fist

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18
Q

Location of heart

A

The base is sitting between the space of the 2nd and 3rd ribs whilst the apex will be sitting in a line from the midclavicular line and we come down to the space between the 5th and 6th ribs and at this point it is approximately where the apex is

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19
Q

PMI

A

Point of maximum impulse - left midvlaviculaar line between the 5th and 6th rib
Called this because the apex as a result of the rotation and tilt is now pointing towards the anterior chest wall between the 5th and 6th ribs so when the heart beats it is banging away on the front of the chest at that space
This is the point where we put the stethoscope to get the loudest and largest heart sound

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20
Q

Orientation of heart

A

Rotated to the left, the base to the posterior - now the apex is pointing towards the anterior, left side of the chest
Left side has been bought around to the posterior and the right towards the anterior so the right ventricle is sitting up against the sternum due to the rotation and the tilt
2/3 of the heart is to the left of the midline due to rotation and tilt

21
Q

Chambers of the heart

A

Four chambered heart

  • The right and left atrium = smaller chambers which quickly put blood into the ventricles
  • The right and left ventricles = larger chambers which pump the blood out of the heart
22
Q

right side…

left side…

A

Deoxygenated

Oxygenated

23
Q

right atrium

A

Receiving chamber. Blood arrives in the right atrium and then drains into the right ventricle

24
Q

right ventricle

A

The lower right chamber of the heart that receives deoxygenated blood from the right atrium and pumps it under low pressure into the lungs via the pulmonary artery.

25
Q

left atrium

A

The left atrium receives oxygenated blood from the lungs and pumps it down into the left ventricle which delivers it to the body.

26
Q

left ventricle

A

The left Atrium recieves oxygenated blood from the lungs and the left Ventricle discharges the oxygenated blood to the rest of the body.

27
Q

interventricular septum

A

Separates the ventricles from one another

28
Q

Superior vena cava

A

The superior vena cava is a vein. It carries deoxygenated blood from the upper half of the body to the right atrium of the heart (e.g. head, chest, upper limbs and neck)

29
Q

Coronary sinus

A

The coronary sinus is a collection of veins joined together to form a large vessel that collects blood from the heart muscle (myocardium). It delivers less-oxygenated blood to the right atrium, as do the superior and inferior venae cavae.

Cardiac veins drain into the coronary sinus which drains into the right atrium

30
Q

Tricuspid valve

A

Separates the right atrium and the right ventricle, 3 leaflet valve

31
Q

Inferior vena cava

A

The inferior vena cava is a vein. It carries deoxygenated blood from the lower half of the body to the right atrium of the heart. (e.g. legs)

32
Q

Pulmonary (semilunar) valve

A

Separates the right ventricle from the pulmonary artery.
When the ventricular chamber relaxes the pulmonary (semilunar) valve shuts and stops the blood in the artery going back down into the ventricular chamber

33
Q

Flow of the right side of the heart

A

right atrium —> right ventricle

  • –> pulmonary trunk
  • -> left & right pulmonary arteries
34
Q

Flow of the left side of the heart

A

left atrium —> left ventricle
—–> ascending aorta
(3 blood vessels branch of the ascending aorta = brachiocephalic, left common carotid and left subclavian)

35
Q

Right pulmonary veins and left pulmonary veins

A

Bring oxygenated blood from the lungs back to the heart back to the left atrium which is the receiving chamber for the pump that drives the systemic circuit.

36
Q

Left atrium flow

A

Oxygenated blood arrives into this chamber (4 openings into the left ventricle), blood then passes from the left atrium to the left ventricle and then is prevented from returning by the left atrioventricular valve (bicuspid valve) (mitral valve), left AV valve stops back flow to the atria so the blow when the left ventricle contracts can only go up through the aortic (semilunar) valve which pushes open and then blood is ejected behind the pulmonary artery into the aorta which is the first artery of the systemic circulation.

37
Q

Aorta

A

Biggest artery and it is the first artery of the systemic circulation

38
Q

Venous returns to the _____ of the Heart

A

Atria (thin walled (receiving) chambers)

39
Q

Right atrium receives…

A

Superior vena cava - everything above diaphragm
Inferior vena cava - everything below diaphragm
Coronary sinus - from the heart muscle itself
(deoxygenated blood)

40
Q

Left atrium receives …

A

Four pulmonary veins which bring oxygenated blood from the lungs

41
Q

Layers of the heart wall

A

Endocardium - layer inside the chambers of the heart
Myocardium - the bulk of the heart wall
Epicardium - layer upon the heart

Percardium (the sac)

42
Q

Epicardium

A

Is the outer layer of the heart wall that runs over the surface

  • Viseral pericardium
  • Loose irregular FCT
  • Blood vessels = Large
  • Adipose
43
Q

Myocardium

A

Heart is a muscular pump hence the bulk of the ventricular wall is myocardium
Muscle of the heart wall which makes up the majority of the wall - middle layer
It is the thickest layer

44
Q

Endocardium

A

A single layer of squamous endothelium within the heart that lines/faces the ventricular chambers. It is made up of:
- Loose irregular FCT- connective tissue support to protect the cells
- Blood vessels = small
Purkinje fibres

Without the cells, the blood would hit the wall of the chamber of the heart or blood vessel and would clot immediately
Endothelial cells are part of the endocardium and also line all the arteries, veins and capillaries

45
Q

Thickness of the right vs left

A

Right side of the heart is thinner than the left. This is because from the right pump you are pushing blood to the lungs (pulmonary circuit) which is a pretty short journey, only have to push the blood a short distance so some pressure is need but you don’t actually need that much force acting on the blood therefore there is less muscle. Whereas the left side of the heart is pushing into the systemic circulation which is everywhere else in the body from head to tow and therefore to do this you need more force and muscle

Still the same volume of blood just different pressures

46
Q

Pericardium

A

The visceral pericardium secretes pericardial fluid into the pericardial cavity which allows the heart to beat in a lubricated environment

The pericardium consists of two layers: a visceral pericardium, which adheres to the external surface of the heart, and a parietal pericardium, in which a fibrous layer is formed by the visceral pericardium reflecting back on itself. The potential space between these two layers is called the pericardial cavity.

Serous pericardial layer secretes the lubricating fluid - parietal layer of the serous pericardium and the visceral layer of the serous pericardium (epicardium)

Made up of a fibrous layer externally

Percardium is not a layer of the heart but part of the sac - made up of a serous pericardium which consists of the visceral pericardium (inner- where fused to epicardium), pericardial cavity (with serous fluid) and parietal pericardium, and the outer fibrous pericardium

47
Q

Atrioventricular valves

A

Controls flow between atrium and ventricles, ensures only unidirectional flow

48
Q

Pericardium and the epicardium relationship

A

Part of the pericardium is part of the epicardium but there are things in the epicardium that are not a part of the pericardium like the coronary arteries and adipose tissue, they are fused together but they are not surrogate terms for each other

Visceral is fused to the epicardium