Lecture 4- Bacterias That Cause Infection Flashcards
How do cytoxins manifest in staphylococcus aureus
Attack cells and cause lesions
Where do haemolysins toxins infect/circulate
Blood
Where do haemolysins toxins infect/circulate
Blood
How do enterotoxins manifest
Affects stomach/GI tract by causing vomiting diarrhea
How do exfoliative toxins manifest
They cause rash, lesions, sores
What enzyme is only present in staphylococcus aureus
Coagulase
How does the enzyme coagulase and penicillinase make staphylococcus aureus a successful pathogen ?
Forms blood clots around bacteria ( which can feed it ) , slows down white blood cells which is our bodies host défense and is naturally defensive against penicillin
What kind of diseases or infections can staphylococcus aureus create ?
- local skin infections leading to postules, boils
-Pneaumonia (lungs)
-food poisoning (stomach)
Describe staphylococcus epidermis
It is an opportunistic pathogen since it’s regularly on our skin, but can cause infection in post operative setting or if it’s not where it should be ie on skin
Normal flora on skin and in mucous
What infections can streptococcus pyogenes(group A)
Strep throat , which can lead to rheumatic heart disease
-skin infections , cellutis
Sepsis (autoiune )
What toxins and antigens cause infections when it comes to group A ( alpha) streptococcus pyogenes
-mainly streptolysis (o and s), macrophages
- spes , scarlet fever rash
What does hyaluronidase produced by streptococcus pyogenes do
It cause bacteria to multiply rapidly causing serious infection and mutated strains
How does flesh . Eating disease work to infect it’s host
Hijacks plasminogen from blood to produce enzyme ( protease) which is good for spreading also codes enzymes which escape while blood cells and immune system
How can streptococcus agalactiae (group B) cause infection
Opportunistic pathogen since,. It is resident flora in vagina. Can pass to baby causing neonatal infection
How does streptococcus feacalis cause infection
Opportunistic pathogen,.it is resident in the GI tract and is resistant to antibiotics. Thus, if someone is taking antibiotics it will kill all thé Luther bactérie in thé GIF tract, allowing them to over populate and “take over “
Viridens streptococci manifestation of infection
.normal flora in oral cavity but, can become opportunistic if A patient undergoes oral surgery and bacteria gets into bloodstream and invades different part of body. Can damage heart values
How does streptococcus pneumoniae cause infection and why is it successful
It can cause pneumonia or meningitis and can produce A capsules protecting itself from immune system
Elderly , alcohols and people in confined spaces are more susceptible
How does neisseria (N) meningitides cause infection
Causes meningitis from sugarcoated capsule which makes this bacteria more pathogenic. The naso-pharynx has this bacteria in healthy quantities.
- can also cause septicaemia, watercourse friedrechsen syndrome
-treatment: penicillin
How does neisseria gonorrhoeae :
Cause infection
- True pathogen, so once entered will cause gonorrhoea
What are symptoms, diagnosis, treatment of gonorrhoea
-Infection of urethra, women are usually asymptomatic
-Men use microscope of urethral swab, women need to grow anal or urethral sample in Petri dishes
- penicillin, but its becoming resistant and bacteria changes often thus no vaccine
