Lecture 4 - Amino acids and primary protein structure Flashcards
Zwitterion: what is it?
A molecule with a negative and positive side
What is the difference between L-amino acid forms and D-amino acid forms?
L-amino acids are used in protein synthesis and is an enantiomers of D-amino acids
Basic amino acid structure
H₂N-CH-COOH
\R
The basic structure of amino acids
H₂N-CH-COOH
\R
Glycine: R group, an interesting fact, shortened form, and what is the fully shortened form?
H
Gly
G
Alanine: R group, an interesting fact, shortened form, and what is the fully shortened form?
CH₃
Ala
A
Valine: R group, an interesting fact, shortened form, and what is the fully shortened form?
CH-CH₃
\CH₃
Val
V
Isoleucine: R group, an interesting fact, shortened form, and what is the fully shortened form?
H₃C-CH-CH₂-CH₃
Ile
I
Leucine: R group, an interesting fact, shortened form, and what is the fully shortened form?
R-CH₂-CH-CH₃-CH₃
Leu
L
Proline: R group, an interesting fact, shortened form, and what is the fully shortened form?
CH₂-CH₂-CH₂-NH₂⁺
This forms a heterocycle within the amino acid where the R group binds with the amine group
Pro
P
Phenylalanine: R group, shortened form, and what is the fully shortened form?
CH₂-benzene
Phe
F
Tyrosine: R group, shortened form, and what is the fully shortened form?
CH₂-benzene-OH
Tyr
Y
Tryptophan: R group, shortened form, and what is the fully shortened form?
CH₂ - C = CH - NH
⠀⠀⠀⠀\CH-CH/
lC₆H₆l
Trp
W
Histidine: R group, an interesting fact, shortened form, and what is the fully shortened form?
CH₂-CH-NH=CH
⠀⠀⠀\CH-NH/
His
H
Arginine: R group, an interesting fact, shortened form, and what is the fully shortened form?
CH₂-CH₂-CH₂-NH-C=NH₂⁺
⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀\NH₂
Arg
R