Lecture 3 PPT Flashcards
Preload is a pressure measured at the end of which phase?
End of phase 1
Afterload is a pressure meadured at the end of which phase?
End of phase 2, beginning of phase 3
Define contractility
The difference in SV if preload and afterload were held constant
What happens to EDV/ SV/ SVR/ CO when preload increases?
They all increase
If afterload is increased, which phase is prolonged?
Phase 2 is prolonged
If afterload is decreased, which phase is shortened? Which is prolonged?
Phase 2 is shortened
Phase 3 is prolonged
How is SV increased when afterload is decreased? What meds do this?
ESV is decreased (more blood pumped out with each beat)
ACE inhibitors, hydralazine
What is the mechanism of action of hydralazine?
The mechanism of action is still unknown
What 2 variables cause decreased ESV?
Increased contractility and decreased SVR
What happens to BP when contractility increases?
BP increases
What happens with LAP with mitral regurgitation?
LAP steadily increases beyond normal throughout systole
In mitral regurgitation, what 2 structures fill the LA during systole?
LV and Pulmonary veins
What happens to EDV and SV with mitral stenosis?
Both are decreased
When does the majority of backflow occur with aortic regurgitation?
End of phase 4 and beginning of phase 1 (when ventricular pressure is lowest and aortic pressure is highest)
With aortic insufficiency, as the ventricle fills during phase 1, does back flow increase or decrease?
Back flow decreases the fuller the ventricle gets (less of a gradient)
What happens to EDV with aortic regurgitation?
Increases