Lecture 3: Gas Exchange and Transport Flashcards

1
Q

what is the respiratory quotient and what is the formula

A
  • metabolic activity of the body in steady state conditions

- Co2 produced / O2 absorbed

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2
Q

what is the respiratory quotient at rest

A

0.8

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3
Q

what is the respiratory quotient for fat metabolism

A

0.7

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4
Q

what is the respiratory quotient for carbohydrate metabolism

A

1.0

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5
Q

what is Fick’s Law

A

rate of gas transfer is:

  • proportional to tissue area
  • difference in partial pressure of the gas
  • inversely proportional to tissue thickness
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6
Q

what does a low V/Q ratio result in

A
  • decreased arterial pO2

- increased arterial pCO2

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7
Q

what does a high V/Q ratio result in

A
  • increased arterial pO2

- decreased arterial pCO2

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8
Q

what is type 2 respiratory failure

A
  • pure underventilation

- increased PaCO2 and proportionate fall in PaO2

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9
Q

what is type 1 respiratory failure

A
  • disturbance in V/Q matching

- fall in PaO2 with no change to PaCO2

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10
Q

what is the partial pressure of oxygen in the air

A

21 kPa

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11
Q

what is the alveolar gas equation

A

PAO2 = PIO2 - (PaCO2/0.8)

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12
Q

what is the normal alveolar arterial gradient in healthy young adults

A

< 2 kPa

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