lecture 3 cell biology Flashcards
In order for cells to function, they must exist in a state of chemical equilibrium T or F
false
How are energetically unfavorable reactions able to occur in cells?
Coupling with the dissociation of activated carriers can make them run.
Reactions are energetically favorable if the change in free energy, DG, is ?
negative
The equilibrium constant for a reaction, as in K = [AB] / [A] [B], is indicative of the strength of binding of the molecular interactions it describes
true
Biological reactions that serve to break down foodstuffs and complex biomolecules (as opposed to those that are biosynthetic) are termed
catabolic
Organisms and cells generate order through their functions, but how do they increase intropy
by relasesing heat
Cells obtain energy from the ________ of organic molecules?
oxidatation
Disorder generated –
DG is negative, therefore its
a ______ reaction
favorable
Km and Vmax are terms describing
Enzyme properties
in coupled enzyme reactions does the delta G change between the individual reactions?
NO, the combination of a favorable and unfavorable reactions can occur because the favorable reaction is really high
ATP is a _____ ______ which means
activated carrier.Reactions can be improved if coupled by high energy activated carrier molecules
ATP can undergo _____ in _ different ways to provide energy to cells
hydrolysis ,2
A common strategy in pathways is to____reaction of the ______ _____ to generate a high _____ intermediate for the reaction that has more favorable reactivity
couple activated carrier energy
in anabolic processes NADPH performs _______
reduction reactions
in catabolic processes NADH performs _______
oxidation reactions
NADPH & NADH are both _____ _____ which use __ & _ as high energy linkages but serve diff. ______
activated carriers, electrons and H+ , roles in the cell
in the activted acrrier Acetyl CoA what is its high energy group
the Acetyl group
in the activted acrrier UDP glucose what is its high energy group
glucose
what is a brief discription of the enzyme cycle
enzyme binds to a substrate, it forms an enzyme substrate complex,catalysis occurs, the enzyme and substrate disassociate
Enzymes change the _____ of reactions, but not the _____ ______ between the species involved
rates, equilibrium point
Km
The ability of an enzyme to associate with (bind) its substrate molecule is best described by
Vmax
is the speed at which and enzyme (bind) with its substrate molecule i
Michaelis-Menton Relationship is about Km and Vmax , Km_____
Vmax as sustrate concentration increaes
limits
Enzymes lower _____ ______ which ____ the number of molecules capable of participating in a reaction
activation energies
increases
