Lecture 3: Bones - Development and Joints Flashcards
what signifies a long bone?
presence of a diaphysis
define diaphysis
elongated/shaft, may have medullary cavity
define epiphysis
ends of a long bone
what separates the epiphysis and diaphysis?
the epiphyseal plate
closed in adults, appears as a line
define periosteum
outer fibrous CT covering bone
the periosteum is continuous with?
CT coverings of muscles, tendons, ligaments
define endosteum
inner lining of medullary cavity
what is the difference between long and short bones?
no shaft in short bones
major types of bones
long short flat irregular sesamoid
what are the types of bone formation?
appositional formation
endochondral bone formation
layers of compact bone laid down on top of spongy bone
appositional growth
in appositional growth, osteoblasts use collagen fibers as …..?
framework to deposit bone matrix
membrane bone formation
growth between skull bones/bones that form walls
no attachments
appositional growth in thickness and diameter
bone forming within and replacing hyaline cartilage
endochondral growth
replacement bone formation
steps involved in endochondral growth
see flow chart…..
blood vessels break through perichondrium and bring……?
osteoprogenitor cells—-which become osteoblasts
after chondrocyte apoptosis…..
they leave behind thin strands as a calcified matrix which osteoblasts use as a framework for laying down osteoid
T/F: Ca deposition is essentially the same as bone formation.
false
bone formation is calcification of osteoid
where are the primary and secondary ossification centers located in endochondral growth?
primary = diaphysis secondary = epiphysis
in the diaphysis bones grow….
in diameter
in the epiphysis bones grow….
in length
aka growth plate
in the center of the diaphysis, cells do what?
osteoclasts break down bone to create the medullary cavity
describe growth in the epiphyseal plate
cartilage is continually added to distal end, as the epiphyseal undergoes endochondral growth
thus bone grows in length
when does growth stop in the epiphyseal plate?
when cartilage in the plate is overtaken by bone