Lecture 3: Biological Designs Flashcards

1
Q

An animals ultimate design determined by nature must address what?

A

The physical demands it faces

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2
Q

Stress

A

Force applied to a material (gravity)

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3
Q

Strain

A

Deformation in a material caused by stress

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4
Q

Scaling effects

A

Consequences of size animal must deal with

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5
Q

Allometry

A

The change in an organism’s shape or proportions concomitant to a change in size

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6
Q

Scaling

A

The study of size and its consequences

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7
Q

Otogenic scaling

A

Scaling related to development

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8
Q

Phylogenic scaling

A

Scaling related to evolutionary relationships

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9
Q

Static Scaling

A

Looking at the organism as it is

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10
Q

How does enlargement of a body part affect an organism?

A

It places additional demands on the organism (often disproportionally)

  1. Mass increases stress on skeletal elements
  2. Increased oxygen and nutritional demands
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11
Q

Units for length

A

mm, cm, or m

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12
Q

Units for area

A

mm^2, cm^2, or m^2

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13
Q

Units for volume

A

mm^3, cm^3, or m^3

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14
Q

Given no change in an organism’s shape, how can even the smallest increments in length affect the area and volume of the body?

A

Area and volume will increase exponentially

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15
Q

How does an increase in volume affect the organism?

A

An increase in volume causes an increase in mass. This may lead to differences (disproportions) between the body and appendages.

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16
Q

Scaling independent features

A

A biologic feature independent of overall size and mass of the organism

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17
Q

What features are relatively independent of the effects of scaling?

A
  1. Size of red blood cells between organisms
  2. Muscle strength per square inch
  3. Biochemical properties of blood
  4. Body temperature
  5. Rate of muscle contraction
  6. The proportion of blood that is red blood cells and liquid plasma
18
Q

Isometric

A

Two bodies (or two body parts) with the same proportions. Example: Legs

19
Q

Allometric

A

Two bodies (or parts of bodies) with different proportions (that is, non-isometric), that changes in proportion to mathematical or natural rules

20
Q

What does the allometric equation (Y=bx^a) represent?

A
Y = one of a paired measurement
X = the second of a paired measurement, plotted on exponential axis
b= constant (Y intercept)
a = slope
21
Q

If a~1, what is the allometric relationship?

A
Directly proportional
–Body weight: heart weight
–Body weight: lung weight
–Body weight to blood volume (ml)
–Body weight to skeletal mass
22
Q

Negative allometries (a<1)

A

Relatively slower growing or becoming relatively smaller

–Body size (mass) : metabolic rate

23
Q

Positive allometries (a>1)

A

Relatively faster growing or becoming relatively larger

–Beak length in shore birds: head size

24
Q

Isometry

A

Body parts remain relatively constant as growth occurs or as species evolve

25
Q

What relevance did the Titanotheres have to this unit?

A
  1. The length of the horn on the skull increased with progressive evolutionary forms
  2. Fossil record shows that there was a positive bias in the direction of a larger horn-similar in other horned lineages
  3. This provides advantages in attracting and fighting over mates
26
Q

What does Kleiber’s Law outline?

A

The negative allometric relationship between body mass (weight) and metabolic rate (e.g., oxygen consumption, body heat production).

27
Q

For the mast majority of animals, how does the metabolic rate scale to the animal’s mass?

A

Metabolic rate scales to the ¾ power of the animal’s mass

28
Q

Is basal metabolic rate higher in smaller or larger animals?

A

Smaller

29
Q

What is a key thing basal metabolic rate affects?

A

Nutritional needs

30
Q

Scaling of heart rate

A

Heart rate has negative n ^-¼ relationship (the larger the animal the slower the heart rate)

31
Q

Scaling of life span

A

Lifespan has a positive n^ +1/4 relationship (the larger the animal the longer the life span)

32
Q

What are allometric calculators used for?

A

To determine drug dosing for different sized people (calculated by actual vs. ideal body weight) and animals of different sizes (being careful to consider differences in how drugs are metabolized)

33
Q

What are some physiologic processes that depend on surface area?

A

Digestion, respiration, & chewing

34
Q

Is more or less surface area better in general?

A

More

35
Q

Inertia

A

Every body is maintained in a state of rest until a new force acts to put it into motion. Resistance to change

36
Q

Change in motion is proportional to what?

A

The force put on it

F = ma

37
Q

What are longstanding effects of weight?

A
  1. Deterioration of weight bearing joints (hips, knees etc)
  2. Remodeling of bone
  3. Stress fractures
38
Q

Hypertrophy

A

Increase in the mass of a cell (tissue)

39
Q

Atrophy

A

Loss of tissue substance

40
Q

How does biological design effect evolution?

A

Mutations arise, provide a source of genetic variation in an organisms traits. Natural selection acts on these traits, favoring those that are compatible with current environmental conditions and acting against traits that are not compatible