Lecture 3 Flashcards
What are the 2 features of the nervous system ?
- CNS
- PNS
What does the CNS contain ?
Brain and spinal cord
What does the PNS contain ?
Nerves and Peripheral ganglia
What is included in the neuroaxis ?
- Dorsal/Superior
- Anterior/Rostral
- Posterior/Caudal
- Ventral/Inferior
- Medial
- Lateral
What is Dorsal/Superior ?
Dorsal: Toward the back, away fron the ventral (stomach side)
Superior: Above another part
What is Anterior/Rostral ?
Toward the front
What is Posterior/Caudal ?
Toward the rear end
What is Ventral/Inferior?
Toward the stomach, away from the dorsal (back) side
What is medial ?
Toward the midline, away from the side
What is lateral ?
Toward the side, awaty from the midline
What is the horizontal plane ?
A plane that shows brain structure as seen from above
What is the saggital plane ?
A plane that shows brain structures as seen from the side
What is the Coronal plane ?
A plane that shows brain strutcture as seen from the front
What is the percentage of gray matter in the brain ?
40
When does gray matter fully develop ?
Once a person reaches their 20’s
What does gray matter do ?
Conducts, processes, and sends information to various parts of the body
What does gray matter contain ?
Contains most of the brains neuronal cell bodies
What is the percentage of white matter in the brain ?
60
What is white matter made up of ?
It is made up of bundles which connect various gray matter areas
When does white matter develop ?
It develops throughout the 20’s and peaks in middle age
What does white matter do ?
Interprets sensory information from various parts of the body
What type of functions does the cortex do ?
- higher-level function
- decision making
- language
What type of functions does the subcortex do ?
where we process more primitive functions
* emotion processed in the amygdala
What is corpus callosum ?
Largest bundle of axons
What is Ipislateral ?
Structures located on the same side of the body/neuraxis
What is Contralateral ?
Structures located on opposite side of the body/neuraxis
What is Broca’s Aphasia ?
- non-fluent aphasia
- damage to the inferior frontal gyrus aka Broca’s area
What is Wernicke’s Aphasia ?
- fluent aphasia
- posterior portion of superior temporal gyrus
What is the function of the forebrain ?
To regulate the body’s physiology and is also responsible for thought and sense perception
What is the function of the midbrain ?
To coordinate responses to light and sound
What is the function of the hindbrain ?
To control many basic bodily functions for survival
What is included in the forebrain ?
- Cerebral Cortex: frontal, parietal, temporal, occipital
- Limbic system: olfactatory bulb, amygdala, hippocampus, cingulate gyrus
- Basal ganglia: striatum ( caudate nucleus, putamen), globus pallidus
- Diencephalon: Thalamus and Hypothalamus
What are the four lobes of the cerebral cortex ?
- Frontal
- Parietal
- Occipital
- Temporal
What is the frontal lobe incharge of ?
abstract reasoning, emotion, personality, decision making, executive function, motor ( precentral gyrus )
What is the parietal lobe in charge of ?
numerical information, and integrates special information, processes sensory info ( postcentral gyrus/primary sensory cortex )
What is the occipital lobe in charge of ?
vision perception ( striate cortex/primary visual cortex damage and cortical blindness )
What is the temporal lobe in charge of ?
auditory information, memory and learning, language, facial recognition, emotion, and motivation
What is the PFC ?
- Prefrontal cortex
- a brain region that modulates high-order (executive) cognitive processes
What is the PFC in charge of ?
- Reasoning
- Problem solving
- Comprehension
- Impulse-control
- Creativity and perserveance
What is cortical homunculus ?
How our bodies are represented in the brain
What is the limbic system ?
Structures that form the epicentre of emotion and behavioural expression
What is the limbic system implicated in ?
- Emotions (fear)
- Anxiety
- Depression
- PTSD
- Alzheimer’s disease
What is the amygdala responsible for ?
Is responsible for emotions, such as fear, and anxiety
What is the hippocampus responsible for ?
Is responsible for memory
What is the basal ganglia ?
Bundles of subcortical nuclei that lie beneath the lateral ventricles, lateral to thalamus
What does the basal ganglia include ?
- striatum ( caudaute nucleus, putamen)
- globus pallidus
What is the responsibility of the basal ganglia ?
- Procedural learning
- Reward system
- important for motor movement
What is basal ganglia implicted in ?
- Parkinson’s
- Schizophrenia
- OCD
What is diencephalon ?
Smaller portion of the forebrain that surrounds the third ventricles
What is the thalamus ?
Projection fibres connect to the cortical surface to relay sensation, spatial, and motor signal information
What is the thalamus responsible for ?
- Acts as a gateway to higher cortical function
- Regulates consciouesness, sleep, alertness
What is the hypothalamus responsible for ?
- Controls the autonomic nervous system and endocrine system
- Fighting, feeding, feeling, mating, sleeping, drinking ( Motivational behaviours )
What is the anterior pituary ?
master gland
Releases tropic hormones that control secretion and production of hormones in other glands of the endocrine system
What is the midbrain ?
mesencephalin
Topmost part of the brainstem, the connection central b/w the brain and the spinal cord
What are the structures included in the midbrain
Tectum and tegmentum
What is the tectum ?
the roof of the midbrain
What is the tegmentum ?
contains nuclei for the 12 cranial nerves and part of the reticular formation
What is substantia nigra ?
Gives rise to the dopamine-containing pathway facilitating readiness for movement
What is included in the hindbrain ?
- Metencephalon: pons and cerebellum
- Myelencephalon: Medulla Oblongata
What do pons do ?
- Directs communication between the cerebellum and the forebrain
- helps control breathing and circulation
What does the medulla oblongata do ?
- Influences the brain centers that regulate sleep and waking
- helps control respiration and circulation
What does the cerebellum do ?
Integrates what we see, hear, and feel; coordinates balance and movement
What 2 nervous systems are within the PNS
Somatic and Autonomic
What does the somatic nervous system do and include?
- controls the movement of skeletal muscles or transmits somatosensory information to the central nervous system from the skin and sense organs
- spinal nerves and cranial nerves
What does the autonomic nervous system do and include ?
- the portion of the PNS that controls the body’s vegetative functions (smooth muscle, cardiac muscle and glands)
- sympathetic nervous system
- parasympathetic nervous system
What are spinal nerves ?
from the vetebral column, fibers travel to muscles or from sensory receptors
What is a dorsal root ?
allow motor neurons to enter spinal cord
afferent axons
What is a ventral root ?
allow motor neurons to exit spinal cord
efferent axons
What are cranial nerves responsible for ?
Sensory/motor function of head and neck
How many pairs of cranial nerves are there ?
12 pairs that are attatched to ventral surface of brain
What occurs in the sympathetic nervous system ?
activation associated with energy expenditure and mobilization
(increased blood pressure, heart rate, epinephrine release)
* fight-or-flight (mobilization)
What occurs in the parasympathetic nervous system ?
processess associated with conserving and restoring energy ( salivation, blood flow to gastrointestinal tract, digestion )
* Rest and Digest (restoration and conservation)
What are the 2 categories for research methods ?
Non-invasive and invasive
What are non-invasive methods ?
- Correlate brain anatomy with behaviour
- Record brain activity during behaviour
What are invasive methods ?
- Examine the effects of brain damage
- Examine the effects of stimulating a brain area
What is phrenology ?
The process of relating skull anatomy to behaviour
What is a computerized tomography (ct scan) ?
Inject dye into the blood and pass X-rays through the head
What is magnetic resonance imaging (MRI) ?
Applies a powerful magnetic field to image the brain
What is a fMRI ?
Modified version of a MRI based on hemoglobin
What is a electroencephalography (EEG) ?
Records electrical activity of the brain thorugh electrodes
What is Near-Infared Spectroscopy (NIRS) ?
Measures the oxygenation levels of cerebral hemoglobin
What is a Magnetoencephalography (MEG) ?
Measures faint magentic responses generated by brain activity
What can brain damage produce ?
inabilty to recognize faces, perceive motion, changes in emotional responses, etc
What is a Postiron Emission Tomography (PET) ?
Provides a high resolution image of brain activity in a living brain
What is lesion ?
damage to brain area, often done for research
What is ablation ?
removal of a brain area
What is Transcranial Magnetic Stimulation (TMS) ?
application of an itnense magnetic field to a portion of the scalp to temporarily deactivate neurons below the magnet
neurostimulator
What is Transcranial Direct Current Stimulation (tDCS) ?
Passes small electric current ( 1 - 2 mA) through the scalp, skull, and meninges to stimulate the brain
Neuromoderator
What is a stereotaxic instrument ?
used percisely to identify brain structures
What is optogenetics ?
A technique that allows researchers to turn on activity in targeted neurons by a device that shines light on the brain using a laser