lecture 3

Question 1

how to find dom alleles?

Answer 1

• Dominant alleles
  
  • Assuming HWE, we calculate q from taking the square root of q2
  • p=1-q
    Once the assumtption is made, you cant test for equilibrium, the observed and expected numbers will be the same

Question 2

how to find dom alleles?

Answer 2

• Dominant alleles
  
  • Assuming HWE, we calculate q from taking the square root of q2
  • p=1-q
    Once the assumtption is made, you cant test for equilibrium, the observed and expected numbers will be the same

Question 3

what do you do when there are more than 2 alleles?

Answer 3

assign p q and r
use forumla
(P+Q+R)2 = 1
2pr and 2qr

Question 4

hoe do ABO blood groups work. is dominant always most freq?

Answer 4

• Many variants
  ○ A and B are codominant to one another
  ○ A and B are dominant to O
  - Can take blood from everyone but can give only A or B
  ○ A person who phenotypically has A blood may have the AA genotype or the AO genotype.
  § A person who phenotypically has B blood may have the BB genotype or the BO genotype.
  DOMINANT DOES NOT AUTOMATICALLY MEAN HIGHER FREQUENCY