Lecture 3

Question 1

Niesseriae is gram-positive cocci

A- true
B- false

Answer 1

False, is gram-negative diplococci

Question 2

Important human pathogens in genus Neisseriae : …. , …..

Answer 2

N.gonorrheae (gonococci), N. Meningitides (meningococci)

Question 3

N. gonorrheae and N. meningitides occur as commensals in the oro-pharynx, naso-pharynx and vagina.

A- true
B- false

Answer 3

False, other members of Neisseriae

Question 4

Not all Niesseriae oxidase positive

A- true
B- false

Answer 4

False, the all

Question 5

G.r.

The infection of gonorrhea doesn’t involve the adult vagina ..

Answer 5

Because it’s acidity and the presence of normal flora.

Question 6

The most frequent complication is ascending infection of the fallopian tubes causing

Answer 6

Salpingitis and pelvic inflammatory disease

Question 7

An infection that may occur in young females through contaminated towels and toilet seats :

A- Ophthalmia neonatorum
B- vulvovaginitis
C- Gonococcal bacteraemia

Answer 7

B

Question 8

It may occur in rare cases and may result in arthritis.

A- Ophthalmia neonatorum
B- vulvovaginitis
C- Gonococcal bacteraemia

Answer 8

C

Question 9

An eye infection (conjunctivitis) occurring in the newborn during their passage in an infected birth canal.

A- Ophthalmia neonatorum
B- vulvovaginitis
C- Gonococcal bacteraemia

Answer 9

A

Question 10

It may involve the cornea leading to blindness.

A- Ophthalmia neonatorum
B- vulvovaginitis
C- Gonococcal bacteraemia

Answer 10

A

Question 11

Important virulence factors as they mediate attachment to mucosal cells of gonococci

Answer 11

Pili

Question 12

….. is enriched selective medium for Neisseriae.

Answer 12

Thayer-Martin (TM) medium

Question 13

Oxidase test of gonococci

Answer 13

Positive

Question 14

Sugar fermentation of gonococci :

Answer 14

Gonococci ferment glucose (with acid production)

Question 15

Diseases caused by meningococci:

Answer 15

Meningitis and meningococcaemia.

Question 16

Virulence factors of meningococci :

Answer 16

• polysaccharide capsule
• lipopolysaccaride (endotoxin)
• IgA protease

Question 17

In meningococci :
Glucose level —>
Proteins level—>

Answer 17

Decreased

Increased

Question 18

CSF in meningococci turpid due to

Answer 18

Large number of pus celle

Question 19

CSF in meningococci under tension due to

Answer 19

Occurrence of inflammatory reaction in closed space

Question 20

Meningococci is gram-negative diplococci, intercellular and extracellular

A-true
B-false

Answer 20

True

Question 21

Most important 3 causes of pyogenic meningitis

Answer 21

Meningococci, pneumococci and H. influenzae type b

Question 22

Sugar fermentation of meningococci

Answer 22

Meningococci ferment glucose and maltose

Question 23

Culture on simple media can grow in N. meningitides

A- true
B- false

Answer 23

False, can’t grow in N. meningitides

And can grownin commensal Neisseriae

Question 24

Agglutination with specific antimeningococcal sera can be agglutinated in N. meningitides

• true
• false

Answer 24

True but can’t aggutinated in commensal Neisseriae

Question 25

sexually transmitted disease affecting both males and females.

Answer 25

Gonorrhea

Question 26

composed of chocolate agar + antimicrobials.

Answer 26

Thayer-mertin ( TM )

Question 27

tends to occur in epidemic form epidemic cerebrospinal fever (epidemic cerebrospinal meningitis ).

Answer 27

Meningococcal meningitis

Question 28

Oxidase test of meningococci :

Answer 28

Positive

Question 29

Treatment of N. Meningitides

Answer 29

Penicillin G , cephalosporin