Lecture 3 Flashcards
Niesseriae is gram-positive cocci
A- true
B- false
False, is gram-negative diplococci
Important human pathogens in genus Neisseriae : …. , …..
N.gonorrheae (gonococci), N. Meningitides (meningococci)
N. gonorrheae and N. meningitides occur as commensals in the oro-pharynx, naso-pharynx and vagina.
A- true
B- false
False, other members of Neisseriae
Not all Niesseriae oxidase positive
A- true
B- false
False, the all
G.r.
The infection of gonorrhea doesn’t involve the adult vagina ..
Because it’s acidity and the presence of normal flora.
The most frequent complication is ascending infection of the fallopian tubes causing
Salpingitis and pelvic inflammatory disease
An infection that may occur in young females through contaminated towels and toilet seats :
A- Ophthalmia neonatorum
B- vulvovaginitis
C- Gonococcal bacteraemia
B
It may occur in rare cases and may result in arthritis.
A- Ophthalmia neonatorum
B- vulvovaginitis
C- Gonococcal bacteraemia
C
An eye infection (conjunctivitis) occurring in the newborn during their passage in an infected birth canal.
A- Ophthalmia neonatorum
B- vulvovaginitis
C- Gonococcal bacteraemia
A
It may involve the cornea leading to blindness.
A- Ophthalmia neonatorum
B- vulvovaginitis
C- Gonococcal bacteraemia
A
Important virulence factors as they mediate attachment to mucosal cells of gonococci
Pili
….. is enriched selective medium for Neisseriae.
Thayer-Martin (TM) medium
Oxidase test of gonococci
Positive
Sugar fermentation of gonococci :
Gonococci ferment glucose (with acid production)
Diseases caused by meningococci:
Meningitis and meningococcaemia.
Virulence factors of meningococci :
- polysaccharide capsule
- lipopolysaccaride (endotoxin)
- IgA protease
In meningococci :
Glucose level —>
Proteins level—>
Decreased
Increased
CSF in meningococci turpid due to
Large number of pus celle
CSF in meningococci under tension due to
Occurrence of inflammatory reaction in closed space
Meningococci is gram-negative diplococci, intercellular and extracellular
A-true
B-false
True
Most important 3 causes of pyogenic meningitis
Meningococci, pneumococci and H. influenzae type b
Sugar fermentation of meningococci
Meningococci ferment glucose and maltose
Culture on simple media can grow in N. meningitides
A- true
B- false
False, can’t grow in N. meningitides
And can grownin commensal Neisseriae
Agglutination with specific antimeningococcal sera can be agglutinated in N. meningitides
- true
- false
True but can’t aggutinated in commensal Neisseriae
sexually transmitted disease affecting both males and females.
Gonorrhea
composed of chocolate agar + antimicrobials.
Thayer-mertin ( TM )
tends to occur in epidemic form epidemic cerebrospinal fever (epidemic cerebrospinal meningitis ).
Meningococcal meningitis
Oxidase test of meningococci :
Positive
Treatment of N. Meningitides
Penicillin G , cephalosporin
