Lecture 25 - Protein synthesis Flashcards

1
Q

Protein synthesis takes place on

A

ribosomes

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2
Q

Transfer RNA molecules (tRNAs) carry

A

the amino acids to the ribosomes

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3
Q

Messenger RNA (mRNA) carries

A

the message with the genetic code

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4
Q

The 3D structure of tRNAs is _____ shaped

A

L-

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5
Q

Inosine is often found in

A

anticodons

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6
Q

Inosine forms a base pair at the

A

wobble position

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7
Q

Inosine maximize the number of

A

codons that can be read by a particular tRNA molecule

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8
Q

The inosine bases in tRNA are formed by

A

the deamination of adenosine

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9
Q

The first two bases of a codon pair in the

A

standard way

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10
Q

Codons that differ in either of their first two bases must be recognized by

A

different tRNAs

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11
Q

Before the anticodon recognizes the codon, the amino acids must

A

be attached to specific tRNA molecules

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12
Q

The attachment of a given amino acid to a particular tRNA establishes the

A

genetic code

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13
Q

The amino acid must first be _______ in order for protein synthesis to occur

A

activated

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14
Q

The activated intermediates in protein synthesis are

A

amino acid esters

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15
Q

Most ________ mRNAs are polycistronic

A

prokaryotic

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16
Q

Most N-terminal amino acids of proteins in E. coli are

A

methionine

17
Q

In eukaryotes, the initiating amino acid is

A

methionine

18
Q

The start codon in eukaryotes is always

A

AUG

19
Q

Eukaryotes ________ have a Shine-Dalgarno sequence

A

do not

20
Q

Eukaryotes have a _______ sequence instead of a Shine-Dalgarno sequence

A

Kozak

21
Q

The structure of eukaryotic mRNA in the cytoplasm is

A

circular