Lecture 22- Symptoms and signs of respiratory disease Flashcards
many diseases involvinf different parts of the respiratory system
airways
lung parenchma
pulmonary circulation
pleura
chrst wall and neuromusculat
Airways (intrathoracic)
- Asthma
- COPD
- Bronchiectasis
- Cystic Fibrosis
Lung parenchyma
- Pulmonary fibrosis
- Pneumonia
- TB
Pulmonary circulation
• Pulmonary embolism
Pleura (between)
- Pneumothorax
- Pleural effusion
Chest wall shape and neuromuscular
• e.g. kyphoscoliosis, myasthenia gravis
when trying to diagnose a resp condition
- history
- clinical exam
- +- furthrr investigations
Cardinal* Signs and Symptoms of Respiratory Disease
- SoB
- chest pain
- cough
- sputum
- Wheeze/ stridor
- Haemoptysis
dyspnoea is a
subjective awareness of icnrease effort breathing
- Symptom rather than a sign…
- But may be objective evidence i.e. raised RR, accessory muscle use
SoB is very common and variably described
Common to all respiratory conditions
But not specific..e.g. anaemia, heart failure, obesity
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further questions to ask if someone is breathless
- onset, duration, timing
- progression
- precipitating factors
- severity
- e.g. when speaking or when walking
chest pain…..
many potential causes
- pleura
- chest wall
- mediastinal structures
chest pain associated with the pleura
- Infection (causing pleurisy)
- Pneumothorax
- Pulmonary embolism (causing infarct)
chest pain associated with the chest wall
- Rib fracture
- Costochondritis
- Shingles (varicella zoster)
chest pain associated with mediastinal structures
- ACS (acute coronary syndrome)
- Pericarditis
- Oesophagitis/GORD
• Aortic dissection
Pleuritic chest pain
irriation of the parietal pleura
- thoracic or shoulder tip - referred- intercosta nerve/phrenic nerve
- Pleuritic pain
- Sharp
- Often well localised
- Worsens with inspiration, coughing, positional movement
cardiac pain
outline coughing
a short explosive expulsion of air- importantn protective mechanism
–> tirggered by stimulation of mechano and or chemoreceptors within airway e.g. by irriation e.g. inflammation or foregin body
- adduction of VCs
- contraction of itnernal intercostals and abdominal muscles= increased intrthoracic pressure
- abduction of VCs
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cough characteristics to think about
Productive cough = sputum
Character e.g.
Timing
Commonest cause is URTI
But…can be a sign of more serious and/or chronic disease
producitve cough can mean
sputum and haemoptysis
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chronic bronhcitis and COPD sputum
clear sputum- no active infection
Yellow/green sputum (live/dead neutrophils)
infection
Large volumes (yellow/green)could suggest
bronchiectasis
Haemoptysis (blood in sputum)…
potential red flag
cough can be caused by
respiratory causes
non-resp cause
respiratory cause of cough
Any irritation of airways (upper and lower respiratory tract!), lung parenchyma or pleura (acute or chronic)
non-respiratory causes of cough
• LV heart failure (“pink frothy sputum”)
- GORD
- Drugs e.g. ACE-inhibitors
Wheeze and Stridor
Abnormal breath sounds indicating narrowing within the airway causing turbulent air flow
describe what a wheeze sounds like and when it occurs
- high pitched, “musical”
- Mostly on expiration
- Narrowing in intrathoracic airways
- E.g. from bronchial smooth muscle
- contraction, oedema, mucous
- E.g. from bronchial smooth muscle
- Narrowing exacerbated during expiration
- May only be audible with stethoscope
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describe what stridor sounds like and what will cause it
- High pitch, constant, loud
- Mostly on inspiration
- Indicates narrowing in extrathoracic airway (upper airway)
- Supraglottis, glottis, infraglottis or trachea
- Narrowing exacerbated during inspiration
- Often audible without stethoscope!
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A 38 year old woman with a history of smoking presents with acute onset of dyspnoea and chest pain…
Oxygen saturations are 90% on air, respiratory rate 28, pulse rate 90, temperature 36.6°C and BP 120/87
A. Pneumonia
B. Acute coronary syndrome
C. Pulmonary embolism
D. Pneumothorax
D
clinical exam
-
inspection
- face
- chest
- hands
-
palpation
- tracheal position
- chest expansion- symmetrical?
-
percussion
- resonant
- hyper-resonant
- dull
- stony-dull
-
auscultation
- normal (vesicular)
- bronchial
- reduced or absent
- added sounds
inspection looking for
- raised RR
- central or peripheral cyanosis
- clubbing
- use of accessory muscles to breath
- pursed lip breathing
- barrel shaped chest
peripheral cyanosis
- Cold exposure and decreased cardiac output
- Slowing of blood to peripheries (due to vasoconstriction)
- Increased oxygen extraction
- More deoxygenated blood present in that area
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Central cyanosis
lips and tongue (mucous membranes)
• Significant cardiac or respiratory cause
• Caused by increase in amount of deoxygenated Hb in blood arriving at tissues [deoxygenated blood is leaving the heart]
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clubbing
is a symptom of disease, often of the heart or lungs which cause chronically low blood levels of oxygen.
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use of accesory muscles to breath
The diaphragm muscle is of the skeletal or striated type and is the major muscle of ventilation. Accessory muscles of ventilation include the scalene, the sternocleidomastoid, the pectoralis major, the trapezius, and the external intercostals.
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pursed lip breathing
Breathing out slowly through mouth with pursed lip
Commonly seen in COPD
how does Pursed lip breathing help
Pursing lips increases resistance to outflow on expiration
Maintains intrathoracic airway pressures allowing for small airways to remain open for longer-
- prolonging period for gas exchange to occur
- and to allowing more air to empty (rather than trap)
Barrel Shaped Chest Increased…..
increased …A-P diameter
- Associated with lung hyperinflation
- Seen in severe COPD (especially emphysema)
- AP diameter > lateral diameter
- Chronic over-inflation of lungs (due to air trapping)
- Hyperexpands the chest wall over time
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tracheal position in pleural effsion
pushes the trachea to the opposite side
tracheal position in pneumothroax
possible if tension
- will push away
how to check symmetry of chest expansion
using both hands on the chest
normal percussion?
resonant
hyper resonant on percussion
increased air e.g. pneumothorax
dull sound on percussion
cosolidation e.g. pneumonia
stony dull sound on percusion
pleural effusion
normal auscultation called
vesicular
- rusting leaves
- inpriation and first part of expiration
- no gap between inspiratory and expiratory components
bronchial sound on auscultation
- ‘Blowing’ harsh sound
- Inspiration and expiration
• Gap between
reduced or absent sound on auscultation
pleural effusion- absent over fluid
asthma- normal or reduced
pneumothorax- absent
added sounds heard on auscultation
- wheeze or stridor
- crackles
- pleural rub
what causes crackles and how can they sound
Snapping open of alveoli/small bronchi
- Fine –> pulmonary fibrosis
- Course –> COPD, bronchiectasis (air bubbling through mucous secretions)
Pleural rub
summary of clinical exam of diff lung conditions
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