Lecture 17- Pleural effusion Flashcards

1
Q

In normal pleural cavity there is tightly controlled

A

production and absorption of pleural fluid.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

pleural cavity lined by

A

mesothelial cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

pleural fluid is absorbed by the

A

lymphatic stoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q
  • Excess fluid in the pleural cavity
A

Imbalance between rate of production and absorption

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

types of pleural effusion

A
  • simple effusion
  • haemothorax
  • chylothorax
  • empyema
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Simple effusion:

A

when there is fluid in the pleural fluid- can be transudate or exudate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

transudate

A

occurs due to icnrease hdyrostatic pressure and low onctoic pressure

i.e. low protein and LDH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

exudate

A

occurs due to ifnlamamtiona nd icnreased capillary permeability

i.e. fluid is high protein and LDH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Haemothorax: §

A

when the fluid is blood e.g. trauma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Chylothorax:

A

when the fluid is lymph (e.g. leak from lymphatic duct)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Empyema:

A

when the fluid is pus (secondary to resistant infection)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Presenting symptoms and signs

*

A
  • SOB (gradual onset)
  • Pleuritic chest pain – irritation of pleural lining to the fluid e.g. blood or lymph
  • Features of clinical disease
    • Congestive cardiac failure – pulmonary oedema
    • Lung malignancy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Signs

A
  • Trachea deviation
    • Away from the affected side
  • Chest movement
    • Reduced on affected side
  • Percussion notes
    • Stony dull on affected side
  • Breath sounds
    • (Vesicular) reduced/ absent on affected side
  • Vocal resonance
    • Reduced on affected side
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

radiological findings: CXR and CT

A

Meniscus showing fluid in the pleural cavity (right base)

  • Beneath the yellow line= fluid
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

causes of a simple effusion

A
  • Pleural fluid
    • Transudate or exudate
  • Investigations
    • Pleural aspiration
      • USS guided procedure
    • Pleural fluid should be colourless
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

causes

Haemothorax:

*

A

when the fluid is blood

  • Trauma
  • After pleural aspiration
    • Red
17
Q

causes Chylothorax

A

when the fluid is lymph (e.g. leak from lymphatic duct

  • Trauma
  • After pleural aspiration
    • Cloudy
18
Q

causes of Empyema

A

when fluid is pus

  • infective cause
  • After pleural aspiration
    • Hard to tell
      • Send fluid off for:
        • Protein levels
        • Glucose levels
        • LDH (lactate dehydrogenase)
        • MC and S
        • pH <7
19
Q

Treatment

A
  • Depending on the cause
  • In very symptomatic pts: chest aspiration
20
Q
  • Recurrent effusions (particularly malignant) may require
A

Indwelling pleural catheter (IPC) for intermittent drainage

Pleurodesis

Aim to allow adequate oxygenation of the lungs for the rest of the body

21
Q

Pleurodesis

A

obliteration of the pleural space

22
Q

main causes of transudate in simple efussion

A

congestive cardiac failure

  • Hypoproteinaemia
    • Nephrotic syndrome
    • Liver cirrhosis
23
Q

main causes of exudate in simple efussion

A

infection (TB, pneumonia), lung malignancy, pulmonary infarction

24
Q

lights criteria of transudate vs exudate

A
25
Q

In general….Transudate

A

- reduced protein (albumin

  • Reduced oncotic pressure
  • More water leaks out of capillaries and into potential spaces such as pleural cavity
26
Q

In general…. Exudate

A

- normal protein (albumin)

  • Protein’s molecules pass through leaky capillary
    • Due to inflammation