Lecture 22: DNA Replication Flashcards

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1
Q

What are DNA polymerase requirements?

A

Requires:

  • all four deoxyribonucleoside triphosphates (dATP, dGTP, dCTP, dTTP)
  • magnesium ions Mg 2+
  • a primer (sequence of bases used to initiate synthesis synthesised by primase). Growing chain only occurs by attaching deoxyribonucleoside mono phosphate to the 3’ OH end of DNA
  • a template strand
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2
Q

DNA polymerase 3 is essential for prokaryotic DNA replication

A

-only DNA polymerase 3 works fast enough to account for the rate of DNA replication in cells

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3
Q

DNA replication by DNA polymerase

A

DNA polymerase synthesize exclusively in the 5’ to 3’ direction
-sands are anti parallel

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4
Q

Much much more in this lecture that is boring as bat shit so need to go over it

A

T

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