Lecture 20: Pulmonary Outcomes and Diagnostics Flashcards

1
Q

what is a dyspnea scale used for

A

measures degree of breathlessness in pts with a pulmonary dx or pts who have primary functional limits from shortness of breath

highly responsive to exertion dyspnea but not as useful for dyspnea at rest

0-4 scale

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2
Q

modified MRC dyspnea scale scores

A

0 = only breathless with strenuous exercise

1= SOB when hurrying on the level or walking uphill

2 = walk slower than other people of the same age on level ground bc of breathlessness or have to stop for breath when walking on my own pace on level ground

3 = stop for breath after walking about 100 meters or after a few min on the level

4 = too breathless to leave the house or breathless when dressing/undressing

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3
Q

describe the BORG dyspnea scale

A

0-10 scale

less specific on functional limit

pt reported

2nd ventilatory threshold at 5-7 on scale

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4
Q

use of 6MWT with pulmonary pts

A

most used submit exercise test

easily converted to METs and VO2 max

American Thoracic Society originally developed

Drop in SpO2 during walk tests is associated with worse outcomes and impaired functional activity tolerance

MCID = 54

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5
Q

6MWT average values and values predictive of hospitalization or mortality for COPD pts

A

average = 380 m

<200m = predictive of hospital/mortality

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6
Q

gait speed use for pulmonary population

A

almost perfect measure

can be assessed in all settings

MCID in pulm rehab = 0.08-0.11 m/s

only outcome measure that provides data related to potential discharge locations/ambulatory locations/etc

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7
Q

gait speed cut off scores for COPD pts

A

slow = <0.8 m/s

normal = >/= 0.8 m/s

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8
Q

what is St. George’s Respiratory Questionnaire (SGRQ)

A

designed to measure impact of overall health, daily life, and perceived well being in pts with obstructive airway disease

combines frequency and severity of symptoms with activities that are limited by breathlessness

scored out of 100

higher scores = more limits

MCID = 4 for minimal improvement, 8 for moderate, 12 for high

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9
Q

what is a chest x-ray and that does it show

A

static view

shows air, fat, fluid, bone, other tissues

air = black

fat, fluid, bone, and other tissues = variations from gray to white

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10
Q

chest x-ray views

A

anterior to posterior = frontal plane

lateral = sagittal plane

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11
Q

indications for a chest X-ray

A

first line of imaging for any respiratory distress

suspicion for pulmonary pathology

post line or device placement

post intubation or extubation

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12
Q

what is the costophrenic angle

A

junction of the costal diaphragmatic and pleural surfaces

should be a sharp angle ~30 degrees

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13
Q

when is a CT used in pulmonary cases

A

used to identify structural defects of the lungs or pulmonary vasculature

more detailed than CXR

can be performed with or without IV contrast depending on indication and comorbidities

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14
Q

indications for CT scan with pulmonary pts

A

lung cancer
ARDS/Covid
any bleeding
structural details

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15
Q

when is a CTA used in pulmonary cases and how does it work

A

radiopaque IV contrast injected prior to CT scan

shows vascular abnormalities or perfusion deficits (vascular obstruction, filling defects, impairments in flow rate)

first line of imaging used to diagnose PE

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16
Q

CTA indications for pulmonary pts

A

PE

ARDS

IPF

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17
Q

when is a PET scan used in pulmonary cases

A

nuclear imaging that can detect glucose uptake, blood flow, and pulmonary metabolism

noninvasive, used to assess for presence of lung tumor metastasis in thoracic cavity

not as accessible as other scans (CT/MRI), expensive, requires equipment

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18
Q

when is a MRI used with pulmonary pts

A

evaluates pulmonary anatomy, thoracic cavity structures, pulmonary blood flow

similar diagnostic accuracy as PET imaging but less expensive and more available

MRA = magnetic resonance angiogram (MRI with contrast to evaluate vasculature)

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19
Q

MRI indications for pulmonary pts

A

any conditions involving bone, mm, fat of thoracic cavity

pre-op for sx guidance

lung cancer

20
Q

what is a ventilation perfusion scan (V/Q scan)

A

ventilation = air in lungs
perfusion = blood in lungs

measures ventilation
- xenon gas inhaled and pt holds breath
- V scans over lung fields and can see Xenon gas

measures perfusion
- radioactive IV contrast injected
- Q scans over lung fields can see where the blood is perfusing

21
Q

when is a V/Q scan indicated

A

PE

IPF/ARDS

22
Q

how are V/Q scans quantified and what do certain results indicate

A

scans occur simultaneously and result with a ration of V to Q

both V and Q are greater in lung bases than apex normally

perfusion defect with normal ventilation = suggests PE

ventilation defect with normal perfusion = suggestive of alveolar fibrosis/destruction or airway obstruction

23
Q

what is a bronchoscopy

A

fiber optic eval of lower respiratory tract; usually trachea/bronchi/segmental bronchi

flexible optic scope inserted through nose or mouth to show airways

24
Q

indications for a broncoscopy

A

visualizing bronchial structures

foreign object removal or biopsy

clearing out of secretions

taking cultures of secretions for infection identification

25
Q

when is arterial blood gas used in pulmonary pts and what is it

A

interpretation of blood pH, PaO2/CO2, HCO3 to compare clinical symptoms and SpO2

indications for pulmonary pts:
- respiratory failure/distress
- altered mental status (AMS)
- to determine O2 delivery device or make changes to mechanical ventilation

26
Q

what is pulmonary function testing (PFT)

A

provides info about airway integrity, respiratory mm function, and condition of lung tissues

allows for diagnosis and classification of pulmonary diseases

classifies as restrictive, obstructive, or mixed etiology

3 types:
- lung volumes
- spirometry
- diffusing capacity

27
Q

what does spirometry measure

A

speed at which air is exhaled

28
Q

what does diffusing capacity measure

A

how well gas diffuses

29
Q

what is body plethysmograph

A

has self contained spirometry measurements

much more accurate than other methods of spirometry since it is a closed system

30
Q

what is forced vital capacity (FVC)

A

max volume of air exhaled as forcefully and as quickly as possible

expressed in liters

most dependent in amount of force (strength) used in early exhalation when lung is most expanded

reduced in both restrictive and obstructive diseases

31
Q

what is forced expiratory volume in 1 second (FEV1)

A

max volume of air exhaled in first second of max exhalation

reflective of airflow in large airways

the Lower the FEV1 %, the more obstructive the disease process

progressive decline linear to worsening of disease

32
Q

what is FEV1/FVC ratio (%)

A

calculation that measure the proportion of the FVC that can be exhaled in the first second of forced exhalation

the lower the ration %, the more severe the obstructive disease

anything less than 70% is abnormal

33
Q

what is diffusing capacity of the lung (DLCO)

A

measures how well gas diffuses across the alveolar-capillary membrane

amount of gas entering pulmonary blood flow per unit of time

expressed as % of gas diffusing into blood

34
Q

describe forced vital capacity for resistive and obstructive diseases

A

R = decreased

O = decreased or normal

35
Q

describe forced expiratory volume in 1 sec (FEV1) for resistive and obstructive diseases

A

R = decreased or normal

O = decreased

36
Q

describe FEV1/FVC ratio for resistive and obstructive diseases

A

R = normal

O = decreased

37
Q

describe total lung capacity for resistive and obstructive diseases

A

R = decreased

O = increased or normal

38
Q

application of PFTs to restrictive disease

A

decreased VC and TLC

biggest limits to functional endurance are decreased inspiratory reserve volume and expiratory reserve volume

39
Q

application of PFTs to obstructive disease

A

increased VC and TLC

biggest limits to functional endurance are increased expiratory reserve volume and residual volume

40
Q

PFT pattern for restrictive disorders (i.e. interstitial lung diseases, IPF, PNA, ARDS, NMD)

A

proportionally decreased FEV1 and FVC

FEV1/FVC near normal

41
Q

PFT pattern for obstructive disorders (i.e. COPD, emphysema, CF)

A

FEV1 < 60%

FEV1/FVC ratio <70%

42
Q

PFT pattern for reactive airways (reversible or partially reversible obstruction like asthma)

A

decrease of FEV1 by 10-20% with activity or trigger

43
Q

what is GOLD staging for COPD

A

used to stratify severity of disease

guides treatment

predictive of functional activity tolerance

values can worsen from baseline if exacerbation occurs

44
Q

what is diffusing capacity of the lung (DLCO)

A

measures integrity of the functional lung unity (respiration/oxygenation)

not a measure of any pulmonary mechanics (ventilation)

abnormal DLCO caused by
- degreased Hgb to carry O2
- increased thickness of alveolar-capillary membrane
- decreased surface area available for gas exchange (main factor)

45
Q

what constitutes mild, moderate, and severe decrease in DLCO values

A

normal = >75% and up to 140%

mild decrease = 60-74%

moderate = 40-59%

severe = <40%